Results 11 to 20 of about 214,356 (305)

Size-selective downstream processing of virus particles and non-enveloped virus-like particles

Frontiers in Bioengineering and Biotechnology, 2023
Non-enveloped virus-like particles (VLPs) are versatile protein nanoparticles with great potential for biopharmaceutical applications. However, conventional protein downstream processing (DSP) and platform processes are often not easily applicable due to
Nils Hillebrandt, Jürgen Hubbuch
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Zika virus like particles elicit protective antibodies in mice. [PDF]

PLoS Neglected Tropical Diseases, 2018
Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness known as Zika fever. Since its recent emergence in 2014 in the American continent, ZIKV infection during pregnancy has been closely associated with a wide range of ...
Mauricio A Salvo, Brock Kingstad-Bakke, Cristhian Salas-Quinchucua, Erwin Camacho, Jorge E Osorio   +4 more
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Production of mosquito cell-derived Zika virus-like particles using BacMos system

Journal of Medical Sciences, 2021
Background: Zika virus (ZIKV) is a mosquito-borne flavivirus which has been conclusively linked to Guillain-Barré syndrome and microcephaly. The worldwide emergence of ZIKV has greatly increased the demand for vaccines that reduce or prevent disease ...
Hui-Tsu Lin, Der-Jiang Chiao, Szu-Cheng Kuo   +2 more
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Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus

Проблемы особо опасных инфекций, 2021
The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva, A. V. Zybkina, A. V. Zaikovskaya, O. V. P’yankov, S. A. P’yankov, A. V. Semenova, G. V. Semenova, D. N. Shcherbakov   +7 more
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How promising are HIV-1-based virus-like particles for medical applications

Frontiers in Cellular and Infection Microbiology, 2022
New approaches aimed at identifying patient-specific drug targets and addressing unmet clinical needs in the framework of precision medicine are a strong motivation for researchers worldwide.
Sofia A. Martins, Joana Santos, Rúben D. M. Silva, Cátia Rosa, Sandra Cabo Verde, Sandra Cabo Verde, João D. G. Correia, João D. G. Correia, Rita Melo   +8 more
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The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F., Nicholls, JM, Bruzzone, R, Chan, C. M., Tsao, SW, Kien, F, Siu, Y. L., Escriou, N, Altmeyer, R., Nal, B., Nicholls, J. M., Chan, CM, Siu, YL, Lo, J, Peiris, J. S. M., Tsao, S. W., Teoh, KT, Nal, B, Teoh, K. T., Peiris, JSM, Altmeyer, R, Lo, J., Escriou, N., Bruzzone, R.   +23 more
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Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]

, 2011
Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Bridge, S., Skinner, Michael A., Anson, Donald, Dennis, M., Simon H Bridge, Dowall, S., Blanchard, Tom J., Getty, B., Stewart, James, Dennis, Mike J., Dowall, SD, Donald S Anson, Anson, D., Dennis, MJ, Bridge, Simon H., Dowall, Stuart D., Blanchard, Thomas, Stewart, JP, Blanchard, T., Skinner, M., Stewart, James P., James P Stewart, Mike J Dennis, Getty, B, Michael A Skinner, Bridge, SH, Bridge, Simon, Sharpe, Sally, Sharpe, SA, Skinner, MA, Getty, Brian, Brian Getty, Dennis, Mike, Blanchard, Tom, Sharpe, Sally A., Anson, DS, Sally A Sharpe, Skinner, Michael, Stuart D Dowall, Tom J Blanchard, Blanchard, TJ, Anson, Donald S., Stewart, J., Sharpe, S., Dowall, Stuart   +44 more
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Minimal system for assembly of SARS-CoV-2 virus like particles

Scientific Reports, 2020
SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian cells.
Heather Swann, Abhimanyu Sharma, Benjamin Preece, Abby Peterson, Crystal Eldridge, David M. Belnap, Michael Vershinin, Saveez Saffarian   +7 more
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Vaccine potential of Nipah virus-like particles. [PDF]

PLoS ONE, 2011
Nipah virus (NiV) was first recognized in 1998 in a zoonotic disease outbreak associated with highly lethal febrile encephalitis in humans and a predominantly respiratory disease in pigs.
Pramila Walpita, Jennifer Barr, Michael Sherman, Christopher F Basler, Linfa Wang   +4 more
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Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]

, 2013
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy   +3 more
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