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Virus-like Particles: Measures and Biological Functions
Viruses, 2022 Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells.
Tara Bhat, Amy Cao, John Yin
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Programmable polymorphism of a virus-like particle [PDF]
Communications Materials, 2022 Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela +4 more
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Platelet-like particles released from Ebola virus-infected megakaryocytic cells behave like virus-like particles. [PDF]
PLoS PathogensEbola virus (EBOV) is likely a zoonotic and re-emerging virus that causes severe outbreaks of Ebola virus disease. The virus spreads to various tissues during the late stage of infection and has been detected in immune-privileged sites of survivors ...
Makoto Kuroda, Peter J Halfmann
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Characterization of chikungunya virus-like particles. [PDF]
PLoS ONE, 2014 Chikungunya virus (CHIKV) is becoming a global concern due to the increasing number of outbreaks throughout the world and the absence of any CHIKV-specific vaccine or treatment.
Nitchakarn Noranate +5 more
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Infection and Drug Resistance, 2023 Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Lee SH, Chu KB, Kim MJ, Quan FS
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Virus-like particles in vaccine development
Expert Review of Vaccines, 2010 Virus-like particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccine candidates. A handful of prophylactic VLP-based vaccines is currently commercialized worldwide: GlaxoSmithKline's Engerix (hepatitis B virus) and ...
Antonio Roldāo +2 more
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Immunogenicity of Virus-like Particles Based on VP1 Protein of Bovine Norovirus [PDF]
Veterinary SciencesBovine Norovirus (BNoV) is a member of the enterovirus family that can cause gastroenteritis in calves. This virus poses a significant risk to calf growth and development as well as to the long-term sustainability of the cattle industry in China and ...
Zhigang Ma +13 more
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Recent Progress on the Versatility of Virus-Like Particles
Vaccines, 2020 Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural proteins of a virus in the absence of genetic material. Having similar morphology to natural viruses but lacking any pathogenicity or infectivity, VLPs have ...
Ciying Qian +10 more
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Production of virus-like particles for vaccines
New Biotechnology, 2017 Virus-like particles (VLPs) are nanostructures that resemble the structures of viruses. They are composed of one or more structural proteins that can be arranged in several layers and can also contain a lipid outer envelope. VLPs trigger a high humoral and cellular immune response due to their repetitive structures. A key factor regarding VLP safety is
Javier Fuenmayor, Laura Cervera
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Analysis of dynamics of human parvovirus B19 virus-like particles [PDF]
, 2023 岩手大学博士（学術）原著論文 Ishida K, Noguchi T, Kimura S, Suzuki H, Ebina H, Morita E. Tracking of Human Parvovirus B19 Virus-Like Particles Using Short Peptide Tags Reveals a Membrane-Associated Extracellular Release of These Particles Journal of Virology 97(2 ...
石田, 幸太郎
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