Results 61 to 70 of about 778,919 (247)

Evaluation of the Thermal Stability of a Vaccine Prototype Based on Virus-like Particle Formulated HIV-1 Envelope

open access: yesVaccines, 2022
The long-term storage stability of vaccines has a major impact on the roll-out and success of global immunization programs. For the Human Immunodeficiency Virus type 1 (HIV-1) virus-like particle (VLP) vaccine prototype evaluated here, nanoparticle ...
Diana Aguado-Garcia   +4 more
doaj   +1 more source

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

open access: yes, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V.   +3 more
core   +2 more sources

Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. [PDF]

open access: yes, 2008
The original publication is available at www.springerlink.comInternational audienceThe mechanisms underlying hepatitis C virus (HCV) morphogenesis remain elusive, but lipid droplets have recently been shown to be important organelles for virus production.
Blanchard, Emmanuelle   +3 more
core   +3 more sources

Virus‐like particles for vaccination against cancer

open access: yesWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2019
Active immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus‐like particle‐based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of ...
Mona O. Mohsen   +3 more
semanticscholar   +1 more source

Investigation of Avian Influenza H5N6 Virus-like Particles as a Broad-Spectrum Vaccine Candidate against H5Nx Viruses

open access: yesViruses, 2022
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4 viruses have been reported to be the source of infections in several outbreaks in the past decades.
Yu-Hsuan Yang   +4 more
doaj   +1 more source

Virus-Like-Vaccines against HIV

open access: yesVaccines, 2018
Protection against chronic infections has necessitated the development of ever-more potent vaccination tools. HIV seems to be the most challenging foe, with a remarkable, poorly immunogenic and fragile surface glycoprotein and the ability to overpower ...
Anne-Marie C. Andersson   +2 more
doaj   +1 more source

Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]

open access: yes, 2017
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin   +2 more
core   +1 more source

Radiation Brightening from Virus-like Particles [PDF]

open access: yesACS Nano, 2019
Concentration quenching is a well-known challenge in many fluorescence imaging applications. Here we show that the optical emission from hundreds of chromophores confined onto the surface of a virus particle 28 nm diameter can be recovered under pulsed irradiation.
Irina B. Tsvetkova   +4 more
openaire   +3 more sources

Production of virus-like particles for vaccines

open access: yesNew Biotechnology, 2017
Highlights • Virus-Like Particles (VLPs) present several advantages over conventional vaccines which make them attractive for vaccination.• Interest in VLP design and production has been increasing in recent years.• Mammalian cell production approach can
Javier Fuenmayor, F. Gòdia, L. Cervera
semanticscholar   +1 more source

Virus-like particles—universal molecular toolboxes

open access: yesCurrent Opinion in Biotechnology, 2007
Virus-like particles (VLPs) are highly organised spheres that self-assemble from virus-derived structural antigens. These stable and versatile subviral particles possess excellent adjuvant properties capable of inducing innate and cognate immune responses.
Ludwig, Christine, Wagner, Ralf
openaire   +2 more sources

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