Results 61 to 70 of about 778,919 (247)
The long-term storage stability of vaccines has a major impact on the roll-out and success of global immunization programs. For the Human Immunodeficiency Virus type 1 (HIV-1) virus-like particle (VLP) vaccine prototype evaluated here, nanoparticle ...
Diana Aguado-Garcia +4 more
doaj +1 more source
Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V. +3 more
core +2 more sources
Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. [PDF]
The original publication is available at www.springerlink.comInternational audienceThe mechanisms underlying hepatitis C virus (HCV) morphogenesis remain elusive, but lipid droplets have recently been shown to be important organelles for virus production.
Blanchard, Emmanuelle +3 more
core +3 more sources
Virus‐like particles for vaccination against cancer
Active immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus‐like particle‐based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of ...
Mona O. Mohsen +3 more
semanticscholar +1 more source
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4 viruses have been reported to be the source of infections in several outbreaks in the past decades.
Yu-Hsuan Yang +4 more
doaj +1 more source
Virus-Like-Vaccines against HIV
Protection against chronic infections has necessitated the development of ever-more potent vaccination tools. HIV seems to be the most challenging foe, with a remarkable, poorly immunogenic and fragile surface glycoprotein and the ability to overpower ...
Anne-Marie C. Andersson +2 more
doaj +1 more source
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin +2 more
core +1 more source
Radiation Brightening from Virus-like Particles [PDF]
Concentration quenching is a well-known challenge in many fluorescence imaging applications. Here we show that the optical emission from hundreds of chromophores confined onto the surface of a virus particle 28 nm diameter can be recovered under pulsed irradiation.
Irina B. Tsvetkova +4 more
openaire +3 more sources
Production of virus-like particles for vaccines
Highlights • Virus-Like Particles (VLPs) present several advantages over conventional vaccines which make them attractive for vaccination.• Interest in VLP design and production has been increasing in recent years.• Mammalian cell production approach can
Javier Fuenmayor, F. Gòdia, L. Cervera
semanticscholar +1 more source
Virus-like particles—universal molecular toolboxes
Virus-like particles (VLPs) are highly organised spheres that self-assemble from virus-derived structural antigens. These stable and versatile subviral particles possess excellent adjuvant properties capable of inducing innate and cognate immune responses.
Ludwig, Christine, Wagner, Ralf
openaire +2 more sources

