Results 71 to 80 of about 214,356 (305)

Virus-Like Particle Systems for Vaccine Development against Viruses in the Flaviviridae Family

Vaccines, 2019
Viruses in the Flaviviridae family are important human and animal pathogens that impose serious threats to global public health. This family of viruses includes emerging and re-emerging viruses, most of which are transmitted by infected mosquito or tick ...
Shu Hui Wong, Alagie Jassey, Jonathan Y. Wang, Wei-Cheng Wang, Ching-Hsuan Liu, Liang-Tzung Lin   +5 more
doaj   +1 more source

Dynamics of HIV-1 assembly and release. [PDF]

, 2009
Assembly and release of human immunodeficiency virus (HIV) occur at the plasma membrane of infected cells and are driven by the Gag polyprotein. Previous studies analyzed viral morphogenesis using biochemical methods and static images, while dynamic and ...
Kräusslich Hans-Georg, Barbara Müller, William J. Godinez, Bräuchle Christoph, Müller, Barbara, Rohr Karl, Karl Rohr, Godinez, William J., William J Godinez, Lampe Marko, Eils, Roland, Godinez William J., Roland Eils, Rohr, Karl, Lampe, Marko, Ivanchenko Sergey, Lamb, Don C., Don C. Lamb, Marko Lampe, Bräuchle, Christoph, Eils Roland, Lamb Don C., Hans-Georg Kräusslich, Christoph Bräuchle, Kräusslich, Hans-Georg, Sergey Ivanchenko, Ivanchenko, Sergey, Don C Lamb, Müller Barbara   +28 more
core   +1 more source

Special Issue "Virus-Like Particle Vaccines". [PDF]

, 2020
Virus-like particles (VLPs) have become a key tool for vaccine developers and manufacturers [...
Bachmann, Martin F., Vogel, Monique, Monique Vogel, Martin F. Bachmann   +3 more
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Mosquito Cell-Derived Japanese Encephalitis Virus-Like Particles Induce Specific Humoral and Cellular Immune Responses in Mice

Viruses, 2020
The Japanese encephalitis virus (JEV) is the major cause of an acute encephalitis syndrome in many Asian countries, despite the fact that an effective vaccine has been developed.
Yu-Hsiu Chang, Der-Jiang Chiao, Yu-Lin Hsu, Chang-Chi Lin, Hsueh-Ling Wu, Pei-Yun Shu, Shu-Fen Chang, Jui-Huan Chang, Szu-Cheng Kuo   +8 more
doaj   +1 more source

The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]

, 2014
Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core  

Recombinant modified vaccinia virus Ankara generating Ebola virus-like particles [PDF]

, 2017
There are currently no approved therapeutics or vaccines to treat or protect against the severe hemorrhagic fever and death caused by Ebola virus (EBOV). Ebola virus-like particles (EBOV VLPs) consisting of the matrix protein VP40, the glycoprotein (GP),
Wolferstätter, Michael, Gert Zimmer, Mark Suter, Michael Wolferstätter, Zimmer, Gert, Steigerwald, Robin, Suter, Mark, Hubertus Hochrein, Andrea S. Laimbacher, Marieken Klingenberg, Robin Steigerwald, Chaplin, Paul, Marc Schweneker, Klingenberg, Marieken, Paul Chaplin, Lauterbach, Henning, Hochrein, Hubertus, Laimbacher, Andrea S, Elisabeth M. Schraner, Schraner, Elisabeth M, Wagner, Susanne, Jürgen Hausmann, Hausmann, Jürgen, Susanne Wagner, Schweneker, Marc, Henning Lauterbach, Ulrike Dirmeier, Dirmeier, Ulrike   +27 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Applying lessons from human papillomavirus vaccines to the development of vaccines against Chlamydia trachomatis

Expert Review of Vaccines, 2018
Introduction: Chlamydia trachomatis (Ct), the most common bacterial sexually transmitted infection (STI), leads to pelvic inflammatory disease, infertility, and ectopic pregnancy in women.
Kathryn M. Frietze, Rebeccah Lijek, Bryce Chackerian   +2 more
doaj   +1 more source

Production in yeast of pseudotype virus-like particles harboring functionally active antibody fragments neutralizing the cytolytic activity of vaginolysin

Microbial Cell Factories, 2011
Background Recombinant antibodies can be produced in different formats and different expression systems. Single chain variable fragments (scFvs) represent an attractive alternative to full-length antibodies and they can be easily produced in bacteria or ...
Pleckaityte Milda, Zvirbliene Aurelija, Sezaite Indre, Gedvilaite Alma   +3 more
doaj   +1 more source