Results 61 to 70 of about 214,356 (305)

Mechanical tuning of virus-like particles

Journal of Colloid and Interface Science, 2023
Hypothesis: Virus-like particles (VLPs) are promising scaffolds for developing mucosal vaccines. For their optimal performance, in addition to design parameters from an immunological perspective, biophysical properties may need to be considered.
Radiom, Milad, Keys, Tim, Turgay, Yagmur, Ali, Ahmed, Preet, Swapan, Chesnov, Serge, Lutz-Bueno, Viviane, Slack, Emma, Mezzenga, Raffaele   +8 more
openaire   +3 more sources

Tomato marchitez virus, a new plant picorna-like virus from tomato related to tomato torrado virus

, 2008
A new virus was isolated from a tomato plant from the state of Sinaloa in Mexico. This plant showed symptoms locally known as `marchitez disease¿: severe leaf necrosis, beginning at the base of the leaflets, and necrotic rings on the fruits.
Verbeek, M., Dullemans, A.M., Heuvel, J.F.J.M., van den, Maris, P.C., Vlugt, R.A.A., van der   +4 more
core   +1 more source

Immunization against active ghrelin using virus-like particles for obesity treatment. [PDF]

, 2013
Ghrelin is a gut hormone that stimulates food intake. In physiological conditions, ghrelin plasma levels rise with fasting and decrease after meals. Obese individuals have low fasting ghrelin levels that rise after food restriction, which is pointed out ...
Carreira, Marcos, Ribeiro, Andreia M, Roy, Polly, Andrade, Sara, Casanueva, Felipe F, Monteiro, Mariana P, Pinho, Filipa   +6 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Post-authorisation experience and reported adverse events following use of a virus-like particle chikungunya vaccine, United States and Germany, up to August 2025

Eurosurveillance
Older adults are at increased risk of severe chikungunya. Some countries advise against vaccinating ≥ 60 or ≥ 65-year-olds with the licenced live-attenuated vaccine (CHIKV LA, IXCHIQ), following severe adverse event (SAE) reports.
Florian Lienert
doaj   +1 more source

Role of nonstructural protein NS2A in flavivirus assembly

, 2008
Flavivirus nonstructural (NS) proteins are involved in RNA replication and modulation of the host antiviral response; however, evidence is mounting that some NS proteins also have essential roles in virus assembly.
Pijlman, G.P., Leung, J.Y., Khromykh, A.A., Hyde, J., Kondratieva, N., Mackenzie, J.M.   +5 more
core   +1 more source

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Harnessing Nanoparticles for Immunomodulation and Vaccines

Vaccines, 2017
The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B.
Ariane C. Gomes, Mona Mohsen, Martin F. Bachmann   +2 more
doaj   +1 more source

Author Correction: Minimal system for assembly of SARS-CoV-2 virus like particles

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Heather Swann, Abhimanyu Sharma, Benjamin Preece, Abby Peterson, Crystal Eldredge, David M. Belnap, Michael Vershinin, Saveez Saffarian   +7 more
doaj   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source