Results 281 to 290 of about 3,690,281 (384)

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

An orally available M^pro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo. [PDF]

Nat Commun
Shuai H, Qiao J, Yoon C, Zhang G, Hou Y, Xia X, Wang L, Deng X, Wang Y, Li Q, Du L, Liu Y, Zhou M, Wong HT, Hu J, Liu H, Hu B, Wang D, Su J, Pan Y, Ye Y, Chen Y, Fang Z, Xia Z, Chai Y, Shi J, Wang Y, Zhu T, Zhang H, Yuan S, Zhou J, Chan JF, Yuen KY, Xu C, Lei J, Yang S, Chu H.   +36 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Construction and validation of a nomogram prediction model for antiviral efficacy based on clinical characteristics and intestinal microflora distribution in patients with chronic hepatitis B. [PDF]

Front Med (Lausanne)
Wu H, Yue M, Wang T, Wei X, Wang Y, Si C.   +5 more
europepmc   +1 more source

Rapid quantification of semen hepatitis B virus DNA by real-time polymerase chain reaction

, 2005
Weiping Qian
openalex   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Development and validation of a dynamic light scattering-based method for viral quantification: A straightforward protocol for a demanding task. [PDF]

PLoS One
Navarro-Lopez RA, Silva-Campa E, Santos-López G, Garibay-Escobar A.   +3 more
europepmc   +1 more source

Super‐Resolution Microscopy in Tissue Engineering

Advanced Materials Interfaces, EarlyView.
Super‐resolution microscopy (SRM) has advanced tissue engineering by providing nanoscale insights into cellular interactions. It reveals detailed cell membrane structures, tracks vesicle and virus entry, and visualizes the cytoskeleton. SRM also improves understanding of cell migration, facilitating tissue regeneration, vascularization, immune ...
Navid Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +2 more
wiley   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Method validation and assessment of the biodistribution and shedding for adenovirus vector-based vaccine using qPCR and dPCR. [PDF]

Mol Ther Methods Clin Dev
Tanaka Y, Hamano S, Ishii-Watabe A, Saito Y, Kikura-Hanajiri R.   +4 more
europepmc   +1 more source