Results 41 to 50 of about 3,645,587 (361)

Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes

Vaccines, 2020
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2, a new member of the genus Betacoronavirus, is a pandemic virus, which has caused numerous fatalities, particularly in the elderly and persons with underlying morbidities. At present, there
F. Zettl, T. Meister, T. Vollmer, Bastian Fischer, J. Steinmann, A. Krawczyk, P. V’kovski, D. Todt, E. Steinmann, S. Pfaender, G. Zimmer   +10 more
semanticscholar   +1 more source

Immunoplaque Assay (Influenza Virus)

Bio-Protocol, 2013
Despite developed long time ago, plaque assay is still the gold standard for viral titer quantification in modern virology. The standard crystal violet-based plaque assay relies on virus’ ability to induce cytopathic effect (CPE) which limits the assay ...
Victor Tse, Yueting Zhang, Gary Whittaker   +2 more
doaj   +1 more source

Zika virus impairs the development of blood vessels in a mouse model of congenital infection [PDF]

, 2018
Zika virus (ZIKV) is associated with brain development abnormalities such as primary microcephaly, a severe reduction in brain growth. Here we demonstrated in vivo the impact of congenital ZIKV infection in blood vessel development, a crucial step in ...
A Javaherian, A Vasudevan, C Leventhal, C Li, CB Coyne, D Butler, EA Logsdon, FL Bookstein, GE Vates, H Gerhardt, H Li, H Retallack, H Tang, HM Lazear, J Mlakar, JJ Miner, JM Stenman, K-Y Wu, L Cui, M Machado-Pereira, M Zou, MC Mladinich, N Salmaso, P Carmeliet, PN Gonzalez, PP Garcez, PP Garcez, Q Shao, Q Shen, Q Shen, R Daneman, RS Lanciotti, S Rounioja, SC Noctor, TD Palmer, TJ Nowakowski, U Sagheer, X Qian   +37 more
core   +3 more sources

Myxoma Virus: Propagation, Purification, Quantification, and Storage [PDF]

Current Protocols in Microbiology, 2010
AbstractMyxoma virus (MYXV) is a member of the Poxviridae family and prototype for the genus Leporipoxvirus. It is pathogenic only for European rabbits, in which it causes the lethal disease myxomatosis, and two North American species, in which it causes a less severe disease. MYXV replicates exclusively in the cytoplasm of the host cell.
Dorothy W. Smith, Grant McFadden, Masmudur M. Rahman, Sherin Smallwood   +3 more
openaire   +3 more sources

Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]

, 2016
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J., Baré, Patricia, De Giorgi, Valeria, Grandinetti, Teresa, Matsuura, Kentaro, Salam, Kazi Abdus, Schechterly, Cathy, Wang, Richard   +7 more
core   +1 more source

Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2

Viruses, 2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes COVID-19 and is responsible for the ongoing pandemic. Screening of potential antiviral drugs against SARS-CoV-2 depend on in vitro experiments, which are based on the quantification of ...
Julia Werner, Raphael M. Kronberg, Pawel Stachura, Philipp N. Ostermann, Lisa Müller, Heiner Schaal, Sanil Bhatia, Jakob N. Kather, Arndt Borkhardt, Aleksandra A. Pandyra, Karl S. Lang, Philipp A. Lang   +11 more
doaj   +1 more source

Cellular IP₆ Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP₆ Are Attenuated for Infection and Replication [PDF]

, 2019
Summary: HIV-1 hijacks host proteins to promote infection. Here we show that HIV is also dependent upon the host metabolite inositol hexakisphosphate (IP6) for viral production and primary cell replication.
Böcking, Till, Faysal, K. M.Rifat, Fletcher, Adam J., Freed, Eric O., James, Leo C., Kleinpeter, Alex, Mallery, Donna L., Novikova, Mariia, Saiardi, Adolfo, Vaysburd, Marina, Wilson, Miranda S.C.   +10 more
core   +3 more sources

Quantitative analysis of particles, genomes and infectious particles in supernatants of haemorrhagic fever virus cell cultures

Virology Journal, 2011
Information on the replication of viral haemorrhagic fever viruses is not readily available and has never been analysed in a comparative approach. Here, we compared the cell culture growth characteristics of haemorrhagic fever viruses (HFV), of the ...
Hedlund Kjell-Olof, Traoré Faye, Adjami Aime, Koivogui Lamine, Manuguerra Jean-Claude, Sall Amadou A, Weidmann Manfred, Lindegren Gunnel, Mirazimi Ali   +8 more
doaj   +1 more source

Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1 [PDF]

, 2019
Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development.
Adamovich, Baggen, Bazzone, Bergelson, Berry, Bladt, Brandenburg, Carthy, Coyne, Coyne, Dodding, Donnelly, Edelman, Fernández-Puentes, Franz, Frischknecht, Fujimoto, Galisteo, Galletta, Glaser, Grøvdal, Hackett, Howlin, Huber, Innocenti, Jacobi, Jiang, Jones, Jose, Karlas, Keszei, Kim, König, Liu, Lupberger, Madshus, Madshus, Mahajan, Mahajan, Mahajan, Massaad, Melnick, Nguyen, Oppliger, Peterson, Porotto, Prieto-Echagüe, Prieto-Echagüe, Rohatgi, Rohatgi, Shen, Staring, Stradal, Teo, Wang, Winston, Wolf, Yamauchi, Yokoyama, Yokoyama, Zerbino   +60 more
core   +2 more sources

Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena) [PDF]

, 2013
Recently, it has been demonstrated that subtype 3 strains of European type porcine reproductive and respiratory syndrome virus (PRRSV) are more virulent/pathogenic than subtype 1 strains. This points to differences in the pathogenesis.
Cao, Jun, Frydas, Ilias, Nauwynck, Hans, Verbeeck, Mieke   +3 more
core   +2 more sources