Results 61 to 70 of about 3,645,587 (361)

Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery. [PDF]

, 2010
Adeno-associated viral (AAV) vectors, which are undergoing broad exploration in clinical trials, have significant promise for therapeutic gene delivery because of their safety and delivery efficiency.
Bethi, SR, Gujraty, K, Jang, J-H, Kane, RS, Koerber, JT, Schaffer, DV   +5 more
core   +2 more sources

Implementation and Validation of the Roche Light Cycler 480 96-Well Plate Platform as a Real-Time PCR Assay for the Quantitative Detection of Cytomegalovirus (CMV) in Clinical Specimens Using the Luminex MultiCode ASRs System. [PDF]

, 2020
Allogenic stem-cell therapies benefit patients in the treatment of multiple diseases; however, the side effects of stem-cell therapies (SCT) derived from the concomitant use of immune suppression agents often include triggering infection diseases.
Li, Shengwen Calvin, Sender, Leonard S, Sparks, Kara J   +2 more
core   +1 more source

Mobility-Based Quantification of Multivalent Virus-Receptor Interactions: New Insights Into Influenza A Virus Binding Mode.

Nano letters (Print), 2019
Viruses, such as influenza A, typically bind to the plasma membrane of their host by engaging multiple membrane receptors in parallel, thereby forming so-called multivalent interactions that are created by the collective action of multiple weak ligand ...
Matthias Müller, D. Lauster, Helen H. K. Wildenauer, A. Herrmann, Stephan Block   +4 more
semanticscholar   +1 more source

Comparison of High-Performance Liquid Chromatography with Sucrose Density Gradient Ultracentrifugation for the Quantification of Foot-and-Mouth Disease Vaccine Antigens

Vaccines, 2022
Foot-and-mouth disease (FMD) causes substantial economic losses in the livestock industry. The protective immunizing component of the FMD virus (FMDV) is a ribonucleoprotein particle with a sedimentation coefficient of 146S.
Ah-Young Kim, Sun Young Park, Sang Hyun Park, Jae Young Kim, Jong Sook Jin, Eun-Sol Kim, Jong-Hyeon Park, Young-Joon Ko   +7 more
doaj   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

Quantification of Torque Teno Virus Viremia as a Prospective Biomarker for Infectious Disease in Kidney Allograft Recipients

Journal of Infectious Diseases, 2018
Quantification of the apathogenic and ubiquitous torque teno virus (TTV) in the peripheral blood predicts infectious disease in recipients of a kidney allograft. TTV might be a potential tool to tailor immunosuppressive drug therapy to prevent infections
R. Strassl, M. Schiemann, K. Doberer, I. Görzer, E. Puchhammer-Stöckl, F. Eskandary, Ž. Kikić, Guido A. Gualdoni, Mathias G. Vossen, S. Rasoul-rockenschaub, H. Herkner, G. Böhmig, G. Bond   +12 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Quantitative Flow Cytometry to Measure Viral Production Using Infectious Pancreatic Necrosis Virus as a Model: A Preliminary Study

Applied Sciences, 2018
In recent decades, flow cytometry (FCM) has become an important tool in virology, due to its applications in viral replication and viral-cell interactions, as well as its capacity to quantify proteins (qFCM).
Diego Vázquez, Carmen López-Vázquez, José G. Olveira, Isabel Bandín, Carlos P. Dopazo   +4 more
doaj   +1 more source

Quantification of the Ability of Natural Products to Prevent Herpes Virus Infection [PDF]

Medicines, 2020
Background: Herpes simplex virus (HSV) is usually dormant and becomes apparent when body conditions decline. We investigated the anti-HSV activity of various natural and synthetic compounds for future clinical application. Methods: Mock- and HSV-infected Vero cells were treated for three days with various concentrations of samples.
Kunihiko Fukuchi, Hiroshi Sakagami, Yoshiaki Sugita, Koichi Takao, Daisuke Asai, Shigemi Terakubo, Hiromu Takemura, Hirokazu Ohno, Misaki Horiuchi, Madoka Suguro, Tomohiro Fujisawa, Kazuki Toeda, Hiroshi Oizumi, Toshikazu Yasui, Takaaki Oizumi   +14 more
openaire   +4 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source