Results 181 to 190 of about 760,800 (362)

A double-edged sword in antiviral defence: ATG7 binding dicer to promote virus replication

Cellular and Molecular Life Sciences
RNA interference (RNAi) and autophagy are two pivotal biological processes that regulate virus replication. This study explored the complex relationship between autophagy and RNAi in controlling influenza virus replication.
Yaotang Wu, Yang Wu, Chenlu Wang, Ningna Xiong, Wenxin Ji, Mei Fu, Junpeng Zhu, Zhixin Li, Jian Lin, Qian Yang   +9 more
doaj   +1 more source

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C -Nucleoside Monophosphate Prodrug [PDF]

, 2014
Joy Y. Feng, Guofeng Cheng, Jason K. Perry, Ona Barauskas, Yili Xu, Martijn Fenaux, Stacey Eng, Neeraj Tirunagari, Betty Peng, Yu Mei, Tian Yang, Yu‐Jen Lee, George Stepan, Leanna Lagpacan, Debi Jin, Magdeleine Hung, Karin S. Ku, Bin Han, Kathryn M. Kitrinos, Michel Perron, Gabriel Birkuš, Kelly A. Wong, Weidong Zhong, Choung U. Kim, Anne Carey, Aesop Cho, Adrian S. Ray   +26 more
openalex   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

In Vitro- and In Vivo-Generated Defective RNAs of Satellite Panicum Mosaic Virus Define cis -Acting RNA Elements Required for Replication and Movement

, 2000
Wenping Qiu, Karen‐Beth G. Scholthof
openalex   +1 more source

Decision letter for "Intercellular movement of plant <scp>RNA</scp> viruses: Targeting replication complexes to the plasmodesma for both accuracy and efficiency"

, 2020

openalex   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Rescue of the Adeno-Associated Virus Genome from a Plasmid Vector: Evidence for Rescue by Replication

, 2003
Peter Ward, Per Elias, R. Michael Linden
openalex   +1 more source

Phosphorylation of Hepatitis C Virus RNA Polymerases Ser29 and Ser42 by Protein Kinase C-Related Kinase 2 Regulates Viral RNA Replication [PDF]

, 2014
Song-Hee Han, Seong-Jun Kim, Eun‐Jung Kim, Tae-Eun Kim, Jae-Su Moon, Geon‐Woo Kim, Seung‐Hoon Lee, Kun Cho, Jong Shin Yoo, Woo Sung Son, Jin‐Kyu Rhee, Seung Hyun Han, Jong‐Won Oh   +12 more
openalex   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Lipid Droplets in Virus Replication

FEBS Letters
Intracellular pathogens rely on host metabolic networks for multiplication. Enveloped viruses need lipids for formation of the viral envelope and positive sense RNA viruses that replicate in membranous inclusions require lipids for formation of the replication compartments.
openaire   +2 more sources