Results 181 to 190 of about 1,825,715 (311)

Fatty acid regulation and phosphatidylethanolamine biosynthesis are important for hepatitis E virus replication. [PDF]

Proc Natl Acad Sci U S A
Yadav KK, Bhandari M, Mahsoub HM, Park YB, Le HV, Choi JM, Brown HM, Rajashekara G, Kenney SP, Meng XJ.   +9 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Discovery of Synthetic Imine-Chalcones Targeting Mayaro Virus Replication. [PDF]

Pathogens
Corrêa-Amorim LDS, Rocha NCD, Barboza GKP, Carlos MFLP, Echevarria A, Rabelo VW, Paixão ICNP.   +6 more
europepmc   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Azathioprine Inhibits Hepatitis A Virus Replication In Vitro. [PDF]

Pathogens
Kanda T, Sasaki-Tanaka R, Abe H, Yokoo T, Sakamaki A, Hayashi K, Kamimura H, Kamimura K, Masuzaki R, Kogure H, Okamoto H, Terai S.   +11 more
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

HIV proviruses with identical sequences arise from cell expansion and infection by a common ancestor virus

Journal of Virus Eradication, 2019
S. Patro, A. Niyongabo, S. Guo, X. Wu, E. Boritz, S. Deeks, F. Maldarelli, S. Hughes, J. Coffin, M. Kearney   +9 more
doaj   +1 more source

c-Fos enhances influenza virus replication by stabilizing the M2 protein and promoting autophagosome accumulation. [PDF]

J Virol
Chen X, Yan J, Li M, Liu H, Lu D, Wang Y, Liu Y, Zhang Q, Gao F, Peng J.   +9 more
europepmc   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Redox-Dependent Activation of Matrix Metalloproteinases Regulates Influenza A Virus Replication in Neuronal Cells. [PDF]

Int J Microbiol
Prezioso C, De Angelis M, Limongi D, Marinelli AM, Frezza F, Nencioni L, Palamara AT, Checconi P.   +7 more
europepmc   +1 more source