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RNA-mediated virus resistance

Current Opinion in Biotechnology, 2002
Post-transcriptional gene silencing is an RNA degradation mechanism that can be induced by viruses. Recent evidence indicates that silencing may also be involved in virus synergism, tissue limitation of virus spread, non-host resistance, virus transmission through seeds and in more general mechanisms of defense such as that mediated by salicylic acid ...
Cecilia, Vazquez Rovere   +2 more
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Antivirals and resistance: influenza virus

Current Opinion in Virology, 2011
Influenza causes annual epidemics of respiratory viral infections are associated with significant morbidity and mortality. Influenza vaccines have been shown to reduce the risk of infection and mitigate against some of the virus' sequellae. Likewise, two classes of antivirals, the adamantanes (amantadine and rimantadine) and the neuraminidase ...
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Strategies for virus resistance in plants

Trends in Genetics, 1989
Virus infections of plants are controlled and suppressed naturally by the action of resistance genes encoded within the plant, by interactions between viruses or even as a result of the activity of functions encoded by or associated with the virus itself.
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Virus Susceptibility and Resistance in Lettuce

2006
Lettuce (Lactuca sativa) is a widely cultivated crop. Historically, the ancient Egyptians cultivated lettuce for its seed oil, which they believed had relaxing and aphrodisiac properties. Later, the Victorian English and others used its latex as a substitute for opium (“lactucarium”).
Candresse, Thierry   +3 more
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Resistance of aged cells to virus replication

Experimental Gerontology, 1979
Abstract The phenomenon of resistance of aged cells to virus replication was investigated in aged L929 cell monolayers infected with Semliki Forest virus. By inhibiting the production and action of interferon, we showed that only about one-third of the 4·5 log restriction in virus replication could be attributed to the antiviral activity of the ...
E, Eylan, A, Gazit
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A Virus-Resistant Network Interface

1993
The concept of an interface for electronic mail between a LAN (Local Area Network) within an organisation and an external network is presented. The interface’s design renders any external intrusion impossible. The concept is based on a straightforward hardware solution and has already been validated by a prototype implementation.
Martin Witte, Wolfgang A. Halang
openaire   +1 more source

Hepatitis C virus and interferon resistance

Microbes and Infection, 2000
Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. It is the only therapy for hepatitis C virus (HCV) infection; however, many virus isolates are resistant. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral ...
D R, Taylor, S T, Shi, M M, Lai
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Virus Drug Resistance

1988
Drug resistance in viruses is generally considered to be an acquired heritable change which is characterised by relief from inhibition by a particular drug. This is always the result of one or more mutations in the virus genome, causing changes in targets for the drug or its metabolites which are reflected in a measurable difference in sensitivity ...
Hugh J. Field, Lindsey J. Owen
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Influenza virus host resistance model

Methods, 2007
Host resistance (HR) models are used to evaluate the effect of a test article on clearance of an infectious microorganism in order to assess total immunocompetence. HR models serve as biomarkers of net immunological health or immunological well-being.
Gary R, Burleson, Florence G, Burleson
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Resistance to Potato virus Y in Potato

2017
Growing potato cultivars resistant to Potato virus Y (PVY) offers the easiest and the most cost-effective solution to prevent the losses caused by PVY. Genes for resistance to PVY can be found in wild and cultivated potato species. Resistance genes functioning on the “gene-for-gene” basis are commonly used in breeding for resistance to PVY, because of ...
Jari P. T. Valkonen   +3 more
openaire   +1 more source

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