This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
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The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
Effect of increased CpG and UpA dinucleotides in the West Nile virus genome on virus transmission by <i>Culex</i> mosquitoes and pathogenesis in a vertebrate host. [PDF]
van Bree JWM +10 more
europepmc +1 more source
Dynamical analysis and numerical assessment of the 2019-nCoV virus transmission with optimal control. [PDF]
Li S +4 more
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Notes from the Field: Hepatitis B Virus Transmission Associated with Assisted Blood Glucose Monitoring in a Skilled Nursing Facility - North Carolina, 2024. [PDF]
Moore JR +8 more
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Impact of Ventilation on Respiratory Virus Transmission in College Residence Hall Cohorts: Potential for Causal Inference About Mode of Transmission. [PDF]
Gold TL +9 more
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Perinatal and Neonatal Chikungunya Virus Transmission: A Case Series. [PDF]
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Tenofovir and Hepatitis B Virus Transmission During Pregnancy: A Randomized Clinical Trial.
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Based on human behavior, immune system functions, and statistical analysis, this paper presents a novel hypothesis for a model for airborne virus transmission. The envisioned model aims to explain the statistical behavior of COVID-19, but also fits to other respiratory viruses. Since it is not possible to do direct experiments with human population and
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