Results 251 to 260 of about 205,339 (347)

Mutations in the E2 Glycoprotein and the 3' Untranslated Region Enhance Chikungunya Virus Virulence in Mice. [PDF]

open access: yesJ Virol, 2017
Hawman DW   +8 more
europepmc   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

open access: yesMolecular Microbiology, EarlyView.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz   +9 more
wiley   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

open access: yesMedical and Veterinary Entomology, EarlyView.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre   +7 more
wiley   +1 more source

PB1 mutations as key drivers of influenza A virus evolution. [PDF]

open access: yesFront Microbiol
Fang C, Sun X, Feng Y, Song H, Wang S.
europepmc   +1 more source

From Culture to Sequencing: Evolving Strategies for the Diagnosis of Pediatric Spondylodiscitis

open access: yesOrthopaedic Surgery, EarlyView.
Diagnostic approaches to pediatric spondylodiscitis have evolved from culture‐based methods with limited sensitivity to advanced molecular and sequencing technologies. Metagenomic next‐generation sequencing (mNGS) enables rapid, culture‐independent pathogen identification, improving diagnostic accuracy, guiding therapy, and reducing invasive procedures
Viola Sbampato   +4 more
wiley   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu   +8 more
wiley   +1 more source

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