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Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Emerging Infectious Diseases, 2017
Unprotected sexual intercourse between persons residing in or traveling from regions with Zika virus transmission is a risk factor for infection. To model risk for infection after sexual intercourse, we inoculated rhesus and cynomolgus macaques with Zika
Andrew D. Haddow, Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo Palacios, Sina Bavari, M. Louise Pitt, Farooq Nasar   +23 more
doaj   +1 more source

Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil

Insect Molecular Biology, Volume 35, Issue 5, Page 526-540, October 2026.
Aedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Ivan Drahun, Jessica M. Sparrow, Cody W. Koloski, Bryan J. Cassone   +3 more
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

When to test for Zika virus [PDF]

As a healthcare provider, you decide if a patient should be tested for Zika virus infection. The algorithm below will help you determine whether or not to test your patient for Zika virus infection.CS289371-I August 3, 2017when-to-test-zika ...

core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Performance of 2 Commercial Serologic Tests for Diagnosing Zika Virus Infection

Emerging Infectious Diseases, 2019
Reliable serologic tests are needed for diagnosis and surveillance of Zika virus infection. We evaluated the Euroimmun and Dia.Pro serologic tests for detection of Zika virus IgM and IgG by using a panel of 199 samples from a region endemic for ...
Séverine Matheus, Cheikh Talla, Bhety Labeau, Franck de Laval, Sébastien Briolant, Lena Berthelot, Muriel Vray, Dominique Rousset   +7 more
doaj   +1 more source

Kunjin Virus, Zika Virus, and Yellow Fever Virus Infections Have Distinct Effects on the Coding Transcriptome and Proteome of Brain-Derived U87 Cells. [PDF]

Viruses, 2023
Brand C, Deschamps-Francoeur G, Bullard-Feibelman KM, Scott MS, Geiss BJ, Bisaillon M.   +5 more
europepmc   +1 more source

Concern over Zika virus outbreak: another alarming global threat

, 2016
Muhammad Yusuf Hafiz,1 Syed Uzair Mahmood,2 Maria Shoaib,1 Farah Hafiz Yusuf1 1Dow Medical College, Dow University of Health Sciences, 2Sindh Medical College, Jinnah Sindh Medical University, Karachi, Pakistan Abstract: Zika virus, as highlighted by the ...
Hafiz MY, Yusuf FH, Shoaib M, Mahmood SU
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source