Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Atypical Influenza A(H3N2) Activity Patterns in Germany, 2021-2023, and Characterization of Newly Emerged Virus Clades. [PDF]
J Med VirolDuwe S +9 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
The systematic use of cost-effectiveness criteria to inform decisions about the removal of items from publicly-financed 'benefits packages'. A report commissioned by the Department of Health and prepared by the London School of Hygiene and Tropical Medicine [PDF]
, 2007 Ettelt, S, Mays, N, Nolte, E, Thomson, S
core
EXPERIMENTS ON INSECT TRANSMISSION OF THE VIRUS OF POLIOMYELITIS [PDF]
, 1912 C. W. Howard, Paul F. Clark
openalex +1 more source
Virioplankton: Viruses in Aquatic Ecosystems
Microbiology and Molecular Biology Reviews, 2000 K. Wommack, R. Colwell
semanticscholar +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Genotype B3.13 influenza A(H5N1) viruses isolated from dairy cattle demonstrate high virulence in laboratory models, but retain avian virus-like properties. [PDF]
Nat CommunFabrizio TP +17 more
europepmc +1 more source
THE LESIONS IN RABBITS EXPERIMENTALLY INFECTED BY A VIRUS ENCOUNTERED IN THE ATTEMPTED TRANSMISSION OF VARICELLA [PDF]
, 1924 Thomas M. Rivers, William S. Tillett
openalex +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source