Results 271 to 280 of about 2,202,818 (359)

Efficient Infection of Nicotiana benthamiana by Tomato bushy stunt virus Is Facilitated by the Coat Protein and Maintained by p19 Through Suppression of Gene Silencing

, 2002
Feng Qu, T.J. Morris
openalex   +2 more sources

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Expansion of the plant-parasitic nematode RNA viruses: Unprecedented diversity, intron-bearing viruses, and cross-kingdom evolutionary links. [PDF]

NPJ Biofilms Microbiomes
Huang H, Mao H, Wu T, Xie J, Zheng J, Cheng J, Fu Y, Cai Q, Lin Y, Chen T, Li B, Yu X, Hsiang T, Jiang D, Xiao X.   +14 more
europepmc   +1 more source

Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member

, 1997
Shaofan Liu
openalex   +2 more sources

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Biogeography and host interactions of CPR and DPANN viruses in acid mine drainage sediments. [PDF]

Nat Commun
Lin ZL, Gao SM, Peng SX, Tang LY, Luo ZH, Lao XW, Zhang SY, Shu WS, Meng F, Huang LN.   +9 more
europepmc   +1 more source

Human and Simian Immunodeficiency Virus Capsid Proteins Are Major Viral Determinants of Early, Postentry Replication Blocks in Simian Cells

, 2002
Christopher M. Owens, Peter Yang, Heinrich G. Göttlinger, Joseph Sodroski   +3 more
openalex   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Epidemiology, evolution, and biological characteristics of avian influenza A (H11) viruses from wild birds. [PDF]

Virulence
Zhao Z, Tian J, Bai X, Li M, Song X, Li J, Shi J, Kong H, Zeng X, Tian G, Liu J, Li C, Chen H, Li Y.   +13 more
europepmc   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source