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Viruses

Current Opinion in Structural Biology, 1996
The structures of the components of large and complex viruses, determined over the past year, have demonstrated the great variation in the ways in which viruses achieve their goals. The structure of the bluetongue virus coat protein provides clues as to how a T = 13 particle is assembled and the structure of the tick-borne encephalitis envelope protein
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Marine Viruses

2016
With an estimated global abundance of 1030, viruses represent the most abundant biological entities in the ocean. There is emergent awareness that viruses represent a driving force not only for the genetic evolution of the microbial world but also the functioning marine ecosystems.
Brussaard, C.P.D.   +2 more
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Inventing Viruses

Annual Review of Virology, 2014
In the nineteenth century, “virus” commonly meant an agent (usually unknown) that caused disease in inoculation experiments. By the 1890s, however, some disease-causing agents were found to pass through filters that retained the common bacteria. Such an agent was called “filterable virus,” the best known being the virus that caused tobacco mosaic ...
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Oncolytic viruses

Nature Reviews Cancer, 2002
Although the cytotoxic effects of viruses are usually viewed in terms of pathogenicity, it is possible to harness this activity for therapeutic purposes. Viral genomes are highly versatile, and can be modified to direct their cytotoxicity towards cancer cells. These viruses are known as oncolytic viruses.
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Phytophthora Viruses

2013
Phytophthora sp. is a genus in the oomycetes, which are similar to filamentous fungi in morphology and habitat, but phylogenetically more closely related to brown algae and diatoms and fall in the kingdom Stramenopila. In the past few years, several viruses have been characterized in Phytophthora species, including four viruses from Phytophthora ...
Guohong, Cai, Bradley I, Hillman
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Oncolytic Viruses

Investigational New Drugs, 1999
Viruses capable of inducing lysis of malignant cells through their replication process are known as "oncolytic" viruses. Clinical trials in oncology have been performed with oncolytic viruses for nearly fifty years. Both systemic and intratumoral routes of administration have been explored.
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Mycoplasma Viruses

CRC Critical Reviews in Microbiology, 1988
Unlike bacterial viruses that infect cells bounded by a cell wall, mycoplasma viruses have evolved to enter and propagate in mycoplasma cells bounded only by a single lipid-protein cell membrane. In addition, mycoplasmas have the smallest amount of genetic information of any known cells, so their complexity is constrained by a limited genetic coding ...
Jack Maniloff, Kevin Dybvig
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