Results 41 to 50 of about 708,539 (311)

Combined high dose vitamin C and E increases oxidative stress and visceral fat mass in rats treated by depot-medroxyprogesterone acetate

Middle East Fertility Society Journal, 2016
Objective: This study was aimed to investigate the effect of combined vitamin C and E on serum leptin, visceral fat mass, and visceral fat oxidative stress in rats treated by depot-medroxyprogesterone acetate (DMPA).
Endang Sri Wahyuni, I. Wayan Arsana Wiyasa, Nurdiana Nurdiana   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents

Journal of Nutrition and Metabolism, 2013
Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods.
Ana Paula Grotti Clemente, Bárbara Dal Molin Netto, Aline di Piano Ganen, Lian Tock, Danielle Arisa Caranti, Marco Túlio de Mello, Sergio Tufik, Ana R. Dâmaso   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A dose-response strategy reveals differences between normal-weight and obese men in their metabolic and inflammatory responses to a high-fat meal [PDF]

, 2014
A dose-response strategy may not only allow investigation of the impact of foods and nutrients on human health but may also reveal differences in the response of individuals to food ingestion based on their metabolic health status.
Buri, C., Vergères, G, Piya, Milan K. (R19111), Portmann, Reto, Kopf, Katrin Annika, Magali Chollet, Caroline Buri, Vionnet, Nathalie, Pralong, Franc̨ois, Laederach, K., Kopf-Bolanz, Katrin A., Chollet, Magali, Egger, L, Reto Portmann, Piya, Milan K, Gijs, Martin A., Buri, Caroline, Milan K. Piya, Egger, Lotti, Piya, Milan K., McTernan, P. G., Piya, M.K., Schwander, Flurina, Mcternan, Philip G., Gijs, MAM, Piya, MK, Gijs, Martin A M, Vionnet, N, Egger, L., Vergères, G., Schwander, F., McTernan, PG, Laederach, K, Lotti Egger, Portmann, R, Chollet, M, Kurt Laederach, Kopf-Bolanz, K.A., Gijs, M.A., Kopf-Bolanz, Katrin A, Schwander, F, Pralong, Francois P., Gijs, Martin A. M., Buri, C, Portmann, R., Vionnet, N., Philip G. McTernan, Chollet, M., McTernan, Philip G, Flurina Schwander, Vergeres, Guy, Nathalie Vionnet, François Pralong, Pralong, F, Kopf-Bolanz, KA, Pralong, F., Martin A.M. Gijs, McTernan, P.G., Guy Vergères, Laederach, Kurt, Katrin A. Kopf-Bolanz   +60 more
core   +2 more sources

FAT-Richtlinie Dynamische Werkstoffkennwerte für die Crashsimulation

, 2022
Im Rahmen des AiF/FAT-Forschungsvorhabens 14205 ist die FAT-Richtline "Dynamische Werkstoffkennwerte für die Crashsimulation" (siehe [1]) zur zuverlässigen Bestimmung von crashrelevanten, dynamischen Werkstoffkennwerten für Crashsimulationen im ...
Blauel, J.G., Luke, M., Böhme, W., Rohr, I., Sun, D.-Z., Harwick, W.   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Low muscle quality in Japanese type 2 diabetic patients with visceral fat accumulation

Cardiovascular Diabetology, 2018
Background Although obesity-related type 2 diabetes mellitus (T2DM) and sarcopenia in the elderly have been increasing worldwide, the associations among visceral fat accumulation, skeletal muscle indices (mass, strength, and quality) and cardiovascular ...
Jun Murai, Hitoshi Nishizawa, Akihito Otsuka, Shiro Fukuda, Yoshimitsu Tanaka, Hirofumi Nagao, Yasuna Sakai, Masahide Suzuki, Shinji Yokota, Hidetoshi Tada, Mayumi Doi, Yuya Fujishima, Shunbun Kita, Tohru Funahashi, Norikazu Maeda, Tadashi Nakamura, Iichiro Shimomura   +16 more
doaj   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source