Results 231 to 240 of about 309,484 (272)

Visceral hypersensitivity

Alimentary Pharmacology & Therapeutics, 2003
SummaryVisceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
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Visceral hypersensitivity in non-erosive reflux disease

Gut, 2007
Non-erosive reflux disease (NERD) is defined as the presence of classic symptoms of gastro-oesophageal reflux disease (GORD) in the absence of oesophageal mucosal injury (or Barrett’s oesophagus) as determined by inspection at upper gastrointestinal endoscopy.1 As such it is regarded as being one of the two main phenotypes of GORD, the other being ...
C H, Knowles, Q, Aziz
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Visceral hypersensitivity in noncardiac chest pain

Gastroenterology Clinics of North America, 2004
Visceral hypersensitivity is a common cause of NCCP. Mechanoreceptors appear to be important in the pathophysiology of NCCP, although chemoreceptors also appear to play a significant role. The processing of visceral information and possibly the development of central sensitization may be important in NCCP, although the pathophysiology of NCCPremains ...
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Mechanisms Underlying Visceral Hypersensitivity in Irritable Bowel Syndrome

Current Gastroenterology Reports, 2011
Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with functional gastrointestinal disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been described in 20%-90% of patients.
BARBARA, GIOVANNI, CREMON, CESARE, DE GIORGIO, ROBERTO, DOTHEL, GIOVANNI, ZECCHI, LISA, BELLACOSA, LARA, CARINI, GIOVANNI, STANGHELLINI, VINCENZO, CORINALDESI, ROBERTO   +8 more
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Evidence for visceral hypersensitivity in high-anxiety rats

Physiology & Behavior, 2000
In patients with irritable bowel syndrome, anxiety is often associated with visceral pain. Based on this information we hypothesized that rats genetically predisposed to anxiety have an increased visceral sensitivity. To test this hypothesis, visceromotor reflex recordings in response to colorectal distention were used to estimate the level of visceral
W D, Gunter, J D, Shepard, R D, Foreman, D A, Myers, B, Greenwood-Van Meerveld   +4 more
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GPER‐mediated, oestrogen‐dependent visceral hypersensitivity in stressed rats is associated with mast cell tryptase and histamine expression

Fundamental & Clinical Pharmacology, 2020
Visceral hypersensitivity (VH) is common in irritable bowel syndrome (IBS), and female patients are more likely to seek healthcare services for IBS‐related abdominal pain.
Shaoxian Xu, Xiaoyang Wang, J. Zhao, Suzhen Yang, Lei Dong, Bin Qin   +5 more
semanticscholar   +1 more source

Visceral hypersensitivity and intolerance symptoms in lactose malabsorption

Neurogastroenterology & Motility, 2007
Abstract  Lactose malabsorption is not always associated with intolerance symptoms. The factors responsible for symptom onset are not yet completely known. As differences in visceral sensitivity may play a role in the pathogenesis of functional symptoms, we evaluated whether an alteration of visceral sensitivity is present in subjects with lactose ...
DI STEFANO, MICHELE, MICELI, EMANUELA, MAZZOCCHI, SAMANTA, TANA, PAOLA, CORAZZA, GINO ROBERTO, Moroni F   +5 more
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Study of visceral hypersensitivity in irritable bowel syndrome

Chinese Journal of Digestive Diseases, 2004
OBJECTIVE:  Visceral hypersensitivity is highly prevalent in most functional bowel disorders, such as irritable bowel syndrome (IBS), and activation of intestinal mast cells (MC) may play a role because they have been found in close proximity to gastrointestinal mucosal sensory nerve terminals containing neuropeptides and a bi‐directional pathway ...
Wen Zhu, Dong, Duo Wu, Zou, Zhao Shen, Li, Xiao Ping, Zou, Ai Yong, Zhu, Guo Ming, Xu, Ning, Yin, Yan Fang, Gong, Zhen Xing, Sun, Xiao Hua, Man   +9 more
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Visceral Pain and Hypersensitivity Disorders

2019
Visceral pain and hypersensitivity disorders are common but poorly understood, and their specific treatment is even more limited than for somatic disorders. Visceral hypersensitivity is mediated by small sensory fibers, the Aδ and C afferents, and results from their lowered activation thresholds, change in phenotype, or altered regional density ...
Rosario Privitera, Praveen Anand
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Anorectal Function and Visceral Hypersensitivity in Celiac Disease

Journal of Clinical Gastroenterology, 2010
To evaluate anorectal function and rectal sensitivity thresholds in patients with celiac disease (CD).In 25 unselected patients with CD (16 female, 9 male; mean age 45, range 24 to 75 y) and 20 controls (12 female, 8 male; mean age 41, range 20 to 65 y) anorectal manometry and rectal balloon distension test were conducted using a 4 lumen water perfused
Agata, Mulak, Ewa, Waszczuk, Leszek, Paradowski   +2 more
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