Results 51 to 60 of about 57,242 (271)

Simultaneous Occurrence of Ocular, Disseminated Mucocutaneous, and Multivisceral Involvement of Leishmaniasis

Case Reports in Infectious Diseases, 2014
Leishmaniasis is a tropical infection caused by the protozoan, belonging to the group of Leishmania which causes Old World and New World disease. These are typically divided into cutaneous, mucocutaneous, visceral, viscerotropic, and disseminated disease.
Cyriac Abby Philips, Chetan Ramesh Kalal, K. N. Chandan Kumar, Chhagan Bihari, Shiv Kumar Sarin   +4 more
doaj   +1 more source

Recent autochthonous cases of leishmaniasis in residents of the Republic of Dagestan, Russian Federation

International Journal of Infectious Diseases, 2019
Eighty years after the last published record of human leishmaniasis from Dagestan, Russian Federation, we report two recent cases which were most probably acquired locally: one case of visceral leishmaniasis in a 2-year old child, and one cutaneous ...
Sergey Andreevich Nagorny, Larisa Alexandrovna Ermakova, Natalia Vladimirovna Golovchenko, Natalia Yurievna Pshenichnaya, Andrey Sergeevich Zhuravlev, Trentina Di Muccio, Luigi Gradoni   +6 more
doaj   +1 more source

Clinical and Immunopathological Aspects of Cutaneous, Mucocutaneous, Visceral, and Post-kala-azar Leishmaniasis

Journal of Zoonotic Diseases, 2023
The disease Leishmaniasis is a neglected illness with two major forms clinically including cutaneous leishmaniasis and visceral leishmaniasis. From almost 100 endemic countries, an estimated one million additional records of leishmaniasis each year are
Basim Saleem Ahmed Al Sulivany, Ahmed Jumaa Ahmed   +1 more
doaj   +1 more source

Seroepidemiology and molecular diversity of Leishmania donovani complex in Georgia [PDF]

, 2016
Background Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. Visceral leishmaniasis (VL), also known as kala-azar, is a potentially fatal disease endemic to large parts of Africa and Asia, and in ...
Adeishvili, Ekaterine, Babuadze, Giorgi, Carrillo, Eugenia, Chakhunashvili, Giorgi, Chanturia, Gvantsa, De Koning, Harry P., Farlow, Jason, Imnadze, Paata, Kalandadze, Irine, Karseladze, Irakli, Kekelidze, Merab, Kokaia, Nora, Markhvashvili, Ivane, Murskvaladze, Mari, Sidamonidze, Ketevan, Tsereteli, David   +15 more
core   +3 more sources

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe, Vishal Satikuvar, Tanjia M. Syeda, Monica Cal, Pascal Mäser, Marcel Kaiser, Hachemi Kadri   +6 more
wiley   +1 more source

Microscopy and Polymerase Chain Reaction Detection of Leishmania chagasi in the Pleural and Ascitic Fluid of a Patient with AIDS: Case Report and Review of Diagnosis and Therapy of Visceral Leishmaniasis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2004
Atypical visceral leishmaniasis is increasingly reported in immunocompromised patients, including patients with AIDS. A case of visceral leishmaniasis in an HIV-infected Brazilian patient with pulmonary and peritoneal involvement is reported ...
Ada RS Diehl, Rodrigo P dos Santos, Ricardo Zimmerman, Letícia P Luz, Tanara Weiss, Pedro Jacobson, Luciano Z Goldani   +6 more
doaj   +1 more source

To determine the sensitivity and specificity of Polymerase chain reaction (PCR) in the diagnosis of visceral leishmaniasis

Sri Lankan Journal of Infectious Diseases, 2014
Introduction: Leishmaniasis is a disease caused by a protozoan parasite of the genus Leishmania, which is transmitted through bites of infected sandflies.
MS ANJUM, U ANSARI, F HUSSAIN, N KALSOOM
doaj   +1 more source

Asymptomatic Leishmania donovani infection and associated factors among blood donors attending at Metema district Blood Bank, Northwest Ethiopia: a cross- sectional study

Archives of Public Health, 2023
Background Ethiopia is one of the top 10 countries in the world where 90% visceral leishmaniasis cases are reported. Metema-Humera lowlands are the most important foci in Ethiopia. Blood transfusion in visceral leishmaniasis endemic foci in Ethiopia does
Iyasu Melkie, Mulat Yimer, Getaneh Alemu, Banchamlak Tegegne   +3 more
doaj   +1 more source

Trend of Visceral Leishmaniasis at Medicine Sans Frontier´s Abdurafi Treatment Center, West Armachiho District, Ethiopia, 2009-2015, a retrospective descriptive analysis

Journal of Interventional Epidemiology and Public Health, 2022
Introduction: Leishmaniasis currently threatens 350 million men, women and children around the world. Visceral leishmaniasis (VL) is a fatal parasitic disease mostly prevalent in low land areas VL typically affects migrant agricultural workers.
Sisay Awoke, Sefonias Getachew, Yimer Seid, Tatek Bogale   +3 more
doaj   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source