Results 71 to 80 of about 57,242 (271)
Visceral Leishmaniasis: Kala-azar [PDF]
A 30-year-old male from rural northwest India presented to our hospital with fever of 4 weeks duration associated with abdominal pain. He was a farmer by occupation and gave history of sleeping in the open. General physical examination showed pallor and subcentimetric cervical lymphadenopathy.
R V, Nampoothiri +3 more
openaire +2 more sources
Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz +24 more
wiley +1 more source
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain +7 more
doaj +1 more source
The use of K39 test in the diagnosis of visceral leishmaniasis [PDF]
From time to time patients admitted with fever of unknown origin prove to be a diagnostic dilemma. While textbooks describe typical symptoms and signs, and also diagnostic tests, these are not always helpful.
Sciberras, Robert
core
Phlebotominae Sand Flies in Paraguay. Abundance Distribution in the Southeastern Region [PDF]
From September 1993 to August 2001, 7,190 phlebotomine were collected with CDC light trap in an endemic area for human leishmaniasis, in the departments of Misiones and Itapúa, Paraguay.
Cousiño, Blanca +6 more
core +3 more sources
Immunobiology of visceral leishmaniasis [PDF]
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found in the spleen, liver, and bone marrow.
Kumar, Rajiv, Nylén, Susanne
openaire +3 more sources
ABSTRACT Cutaneous leishmaniasis is a neglected tropical disease with only one oral treatment option. DNDI‐6148 is an orally bioavailable compound with potent antiparasitic activity in preclinical studies. Establishing skin target‐site pharmacokinetic/pharmacodynamic (PK/PD) relationships is essential to enable its clinical development.
Rasmus Hansen Henninger +7 more
wiley +1 more source
Management of trypanosomiasis and leishmaniasis [PDF]
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford +39 more
core +2 more sources
Diagnosis of visceral leishmaniasis [PDF]
Leishmaniasis is a vector-borne disease with up to 350 million people at risk of infection worldwide. Among its different clinical manifestations, visceral is the most severe form. Since clinical features of visceral leishmaniasis (VL) mimic several other common diseases, accurate diagnosis is crucial as the treatment is associated with significant ...
Pankaj, Srivastava +3 more
openaire +2 more sources

