An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection [PDF]
Jonathan L. M. Fontes +14 more
openalex +1 more source
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini +6 more
wiley +1 more source
Leishmaniasis in rheumatoid arthritis
Leishmaniasis represents a complex of diseases with an important clinical and epidemiological diversity. Visceral leishmaniasis is of higher priority than cutaneous leishmaniasis as it is a fatal disease in the absence of treatment. The clinical spectrum
M. Cutolo, M.E. Secchi, C. Pizzorni
doaj +1 more source
Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area
OBJECTIVE To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State ...
Celina Roma Sánchez de Toledo +5 more
doaj +1 more source
Is Visceral Leishmaniasis the same in HIV-coinfected adults?
Introduction: Visceral Leishmaniasis is the most severe form of disease caused by the Leishmania donovani complex, with significant morbidity and mortality in developing countries.
Guilherme Alves de Lima Henn +7 more
doaj +1 more source
Interstitial pneumonitis in canine visceral leishmaniasis
Forty-one naturally infected dogs with visceral leishmaniasis from an urban area of Corumbá (Mato Grosso do Sul-BRAZIL) were studied and three types of lung involvement due to visceral leishmaniasis were characterized; a cellular, a cellular-fibrotic and
M. I. S. Duarte +5 more
doaj +1 more source
A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. [PDF]
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area.
Boelaert, M +5 more
core +1 more source
Transcription of toll-like receptors 2, 3, 4 and 9, FoxP3 and Th17 cytokines in a susceptible experimental model of canine Leishmania infantum infection [PDF]
Canine leishmaniosis (CanL) due to Leishmania infantum is a chronic zoonotic systemic disease resulting from complex interactions between protozoa and the canine immune system.
A Ives +81 more
core +4 more sources
Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]
Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO +8 more
core +1 more source
Leishmaniasis in the Argentine Republic: Temporal and geographical distribution from 2013 to 2017
Objective: To assess the temporal and geographical distribution of confirmed cases of cutaneous, mucocutaneous and visceral leishmaniasis in the Argentine Republic from 2013 to 2017.
María J Germano +5 more
doaj +1 more source

