Results 111 to 120 of about 91,179 (287)

Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation

Frontiers in Pharmacology, 2017
Neonatal maternal separation (MS) is a major early life stress that increases the risk of emotional disorders, visceral pain perception and other brain dysfunction.
Hui-Li Tang, Hui-Li Tang, Gongliang Zhang, Ning-Ning Ji, Lei Du, Bin-Bin Chen, Rong Hua, Yong-Mei Zhang   +7 more
doaj   +1 more source

IV. Visceral afferent contributions to the pathobiology of visceral pain [PDF]

, 2000
Functional bowel and other visceral disorders exhibit multiple characteristics that suggest the presence of visceral hyperalgesia. The discomfort, pain, and altered sensations (e.g., to intraluminal contents) that define the hyperalgesia typically arise
G. F. Gebhart
core   +1 more source

Arthroscopic and Mini‐Open Combined Medial Patellofemoral Ligament and Medial Patellotibial Ligament Reconstruction for J‐Sign‐Positive Patellar Dislocation

Arthroscopy Techniques, EarlyView.
Abstract This technical note addresses recurrent patellar instability with a positive J‐sign and describes a minimally invasive, arthroscopic and mini‐open approach that combines medial patellofemoral ligament and medial patellotibial ligament reconstruction with extensive lateral retinacular release, positioned as a preferred or transitional option ...
Zirong Huang, Xin Gao, Dewei Xu, Bingran Fan, Yankan Ou, Weimin Zhu   +5 more
wiley   +1 more source

Dual‐Camera Arthroscopic Bone Block Cerclage Technique Using a Tricortical Iliac Crest Autograft for Glenoid Reconstruction in Patients With Anterior Shoulder Instability

Arthroscopy Techniques, EarlyView.
Abstract Arthroscopic‐assisted grafting of the anterior glenoid in instability surgery offers lower morbidity and fewer complications than open techniques but faces challenges in operative field visualization. The 1.9 mm NanoScope (Arthrex, Naples, FL) enables simultaneous arthroscopic views from opposing angles, providing anterior glenoid ...
Joshua C. Y. Ong, Rachel Jayesh Patel, Magnus Arnander, Eyiyemi Pearse, Duncan Tennent   +4 more
wiley   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong, Jungryul Kim, Woojin Jung, Jiyeon Jeon, Hyeongjun Jo, Kyoung‐Bin Ryu, Ja‐Young Hong, Kwan Soo Kim, Seongjun Yang, Hee Young Ju, Hwi‐yeol Yun, Jung‐woo Chae, Keon Hee Yoo, Soyoung Lee   +13 more
wiley   +1 more source

‘School is their whole world’: Teachers' perspectives on loneliness among children and adolescents from England and mainland China

British Educational Research Journal, EarlyView.
Abstract As front‐line observers and active participants in pupils' daily lives, teachers closely monitor pupils' social interactions, emotional states and behavioural changes. Their unique perspective enables them to detect problems in the social lives of their pupils that may not be immediately visible to peers, parents or mental health professionals.
Yixuan Zheng, Charlotte Bagnall, Caroline Bond, Elizabeth Birchinall, Pamela Qualter   +4 more
wiley   +1 more source

No other choice: The fracturing of reflexivity in families' pathways into (non‐)elective home education in England

British Educational Research Journal, EarlyView.
Abstract In England, education is compulsory, but schooling is not: it is legal for families to home educate their children. This form of education is officially termed by the Department for Education as ‘Elective Home Education’. As this designation implies, many families home educate as a positive and preferential ‘choice’.
Katherine Davey, Lisa Russell, Ron Thompson, Jo Bishop   +3 more
wiley   +1 more source

Sex-specific post-inflammatory dysbiosis mediates chronic visceral pain in colitis

Gut Microbes
Background Despite achieving endoscopic remission, over 20% of inflammatory bowel disease (IBD) patients experience chronic abdominal pain. Visceral pain and the microbiome exhibit sex-dependent interactions, while visceral pain in IBD shows a sex bias ...
Maria J. Arzamendi, Yasaman B. Habibyan, Manon Defaye, Adam Shute, Cristiane H. Baggio, Ronald Chan, Christina Ohland, Dominique G. Bihan, Ian A. Lewis, Keith A. Sharkey, Kathy D. McCoy, Christophe Altier, Markus B. Geuking, Yasmin Nasser   +13 more
doaj   +1 more source

Erwin Schrödinger und die Versuchungen der (Wissenschafts‐)Biografik: Vorurteilsgefüge und Mechanismen der Skandalisierung

Berichte zur Wissenschaftsgeschichte, EarlyView.
Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

BMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu, Yongsheng Zhou, Longwei Lv   +8 more
wiley   +1 more source