Results 171 to 180 of about 91,179 (287)

Inside-Out Mechanism of Referred Visceral Pain: Protocol for a Systematic Review of Cutaneous Neurogenic Inflammation in Preclinical Animal Models of Visceral Diseases. [PDF]

JMIR Res Protoc
Yang E, Muñoz-Vergara D, Ahn AC, Lu W, Napadow V, Cronin AE, Wayne PM.   +6 more
europepmc   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Dexmedetomidine-Loaded Hydrogel Microneedles Alleviate Acute Inflammatory Visceral Pain in Mice. [PDF]

Gels
Ke P, Tan X, Zhou Y, Bao X, Wu L, Han M, Wu X.   +6 more
europepmc   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Impact of visceral pain on migraine symptoms in comorbid patients: a retrospective observational study. [PDF]

J Headache Pain
Affaitati G, Costantini R, Wesselmann U, Czakanski P, Lanzara R, Ornello R, Sacco S, Giamberardino MA.   +7 more
europepmc   +1 more source

Improving the Finite Sample Estimation of Average Treatment Effects Using Double/Debiased Machine Learning With Propensity Score Calibration

Journal of Applied Econometrics, EarlyView.
ABSTRACT Double/debiased machine learning (DML) uses for estimating an average treatment effect (ATE) a double‐robust score function that relies on the prediction of nuisance functions, such as the propensity score, which is the probability of treatment assignment given covariates.
Daniele Ballinari, Nora Bearth
wiley   +1 more source

RETRACTION: A Study on THE Mechanism of Electroacupuncture to Alleviate Visceral Pain and NGF Expression. [PDF]

Comput Intell Neurosci
Intelligence And Neuroscience C.
europepmc   +1 more source

The Alignment Risks of AI Overconfidence about Consciousness

Journal of Applied Philosophy, EarlyView.
ABSTRACT Many contemporary AI systems (as of May 2025) have expressed extreme confidence in current and near‐future AI lacking consciousness and moral patiency. This article argues that artificially reinforcing such confidence, even if pragmatically useful, poses a novel alignment risk: as coherence‐seeking AIs become more epistemically principled ...
Sharon Berry
wiley   +1 more source

LncRNA-Associated ceRNA Network in the Spinal Cord Reveals the Central Mechanism of Chronic Inflammatory Visceral Pain. [PDF]

J Pain Res
Li X, Wang X, Dong X, Li Z, Lu Y, Liu L, Yang G, Hong J, Yang Y, Zhang C, Wu H, Zhang D, Ma X.   +12 more
europepmc   +1 more source

The We‐Relationship as a Key to Addressing Dementia‐Related Ambiguous Loss

Journal of Applied Philosophy, EarlyView.
ABSTRACT Pauline Boss describes the challenges faced by people caring for family members with dementia in terms of ambiguous loss – a condition in which the physical presence of the person with dementia coexists with their psychological absence. This article proposes the concept of we‐relationship as a key to addressing dementia‐related ambiguous loss.
Takuya Niikawa, Xue Li
wiley   +1 more source