AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Experimental and coupled quasi-linear viscoelastic biphasic modeling of regional and strain-rate dependent tensile behavior in the temporomandibular joint disc. [PDF]
Sci RepPourbavarasad SS, Hashemi A.
europepmc +1 more source
Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration
Advanced Science, EarlyView.M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang +13 more
wiley +1 more source
Impact of Mono-, Di-, and Trivalent Ions on the Rheology of Borate-Crosslinked Guar Fracturing Fluids. [PDF]
GelsLiu B +8 more
europepmc +1 more source
Advanced Science, EarlyView.EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang +5 more
wiley +1 more source
Gingival Creep Failure: A Viscoelastic Theory of Recession in Thin Periodontal Phenotypes. [PDF]
Biology (Basel)Kuc AE +5 more
europepmc +1 more source
Developing Soft Interconnected Microchannel Network for 2D Skin‐Like Actuator
Advanced Science, EarlyView.A soft interconnected network of microchannels is proposed to develop new pneumatic actuators for future bio‐inspired soft robots. Simultaneous stimulation of this network generates regional asymmetric strains in walls of microchannels whose interaction across the entire surface leads to bending curvatures in multidimensions.
John Noee +4 more
wiley +1 more source
Enhancing Electrical Impedance Based Deformation Sensing with Dielectric Current Guide
Advanced Electronic Materials, EarlyView.This work introduces a dielectric‐based field manipulation strategy for electrical impedance tomography in soft robotics. By using silicone as a passive electric field guide, improved deformation sensing accuracy and reduced interference are achieved without embedding conductive components.
Arsen Abdulali +3 more
wiley +1 more source
Unifying Environmental Stress Cracking and Mechano-Sorptive Creep Under the Umbrella of Mechano-Sorptive Phenomena. [PDF]
Biomimetics (Basel)Yan Y +4 more
europepmc +1 more source
From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications
Advanced Electronic Materials, EarlyView.This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra +2 more
wiley +1 more source