Results 101 to 110 of about 1,982,159 (297)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Detection and identification of ship's hull number for unmanned surface vehicle
Zhongguo Jianchuan YanjiuObjectiveAiming at the problem of ship hull number recognition, this paper proposes a real-time ship's hull number recognition method for unmanned surface vehicles (USVs). MethodsBased on a one-stage object detection model (e.g.
Renran ZHANG, Lei ZHANG, Yumin SU
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Automatic Image Registration in Infrared-Visible Videos using Polygon Vertices
, 2014 In this paper, an automatic method is proposed to perform image registration in visible and infrared pair of video sequences for multiple targets. In multimodal image analysis like image fusion systems, color and IR sensors are placed close to each other
Bilodeau, Guillaume-Alexandre +2 more
core
Seeing the invisible: The scope and limits of unconscious processing in binocular rivalry [PDF]
, 2008 When an image is presented to one eye and a very different image is presented to the corresponding location of the other eye, they compete for conscious representation, such that only one image is visible at a time while the other is suppressed.
Sheng He, Zhicheng Lin
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Pseudocolor transformation of ERTS imagery [PDF]
One of the photographic techniques which shows great promise as an aid in interpreting ERTS imagery is pseudocolor transformation. It is a process where each shade of gray in an original black-and-white image is seen as a different color in the ...
Lamar, J. V., Merifield, P. M.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source