Results 81 to 90 of about 12,775,686 (306)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CBFM: Contrast Balance Infrared and Visible Image Fusion Based on Contrast-Preserving Guided Filter
Infrared (IR) and visible image fusion is an important data fusion and image processing technique that can accurately and comprehensively integrate the thermal radiation and texture details of source images.
Wuyang Liu, Xilai Li, Xiaosong Li
core +1 more source
This study investigated a novel method of fusing visible (VIS) and infrared (IR) images with the major objective of obtaining higher-resolution IR images.
Lei Han +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Difference-Expansion Based Reversible and Visible Image Watermarking Scheme
A reversible image watermarking scheme recovers the original cover image after extracting the embedded watermarks. A visible image watermarking scheme embeds watermarks to create a visible watermark effect on the cover image.
Chien-Chang Chen, Yao-Hong Tsai, Hsin-Cheng Yeh
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Multi-variate image analysis for detection of biomedical anomalies [PDF]
Multi-modal images are commonly used in the field of medicine for anomaly detection, for example CT/MRI images for tumour detection. Recently, thermal imaging has demonstrated its potential for detection of anomalies (e.g., water stress, disease) in ...
Raza, Shan-e-Ahmed
core

