Results 21 to 30 of about 160,879 (219)

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Interpretable deep learning for diagnosis of fungal and acanthamoeba keratitis using in vivo confocal microscopy images

Scientific Reports, 2023
Infectious keratitis refers to a group of corneal disorders in which corneal tissues suffer inflammation and damage caused by pathogenic infections. Among these disorders, fungal keratitis (FK) and acanthamoeba keratitis (AK) are particularly severe and ...
Mahmoud Essalat, Mohammad Abolhosseini, Thanh Huy Le, Seyed Mohamadmehdi Moshtaghion, Mozhgan Rezaei Kanavi   +4 more
doaj   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Factors associated with graft astigmatism after corneal transplantation for keratoconus

BMC Ophthalmology
Background Graft astigmatism remains a major impediment to early visual rehabilitation and the long-term success of keratoplasty. Previous studies have identified graft size, donor–recipient size discrepancy, timing of suture removal, and surgical ...
Sepehr Feizi, Mohammad Ali Javadi, Sina Khosravi Mirzaei, Firouze Hatami, Kia Bayat, Mohammad Abolhosseini, Hamed Esfandiari, Zahra Khorrami   +7 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Postoperative Inflammation and Pain Management with Intracanalicular Dexamethasone Insert: Real-World Applications

Ophthalmology and Therapy
Introduction Transient pain and ocular inflammation may occur with ophthalmic surgery. Pain is an important determinant of patient satisfaction, and inflammation can increase the risk for suboptimal visual outcomes.
Eric D. Donnenfeld, Jordan Graff, Cathleen McCabe, Kendall E. Donaldson, Savak Teymoorian, Trung Tran, Srilatha Vantipalli, Aditi Bauskar, Michael H. Goldstein   +8 more
doaj   +1 more source

LensAge index as a deep learning-based biological age for self-monitoring the risks of age-related diseases and mortality

Nature Communications, 2023
Age is closely related to human health and disease risks. However, chronologically defined age often disagrees with biological age, primarily due to genetic and environmental variables.
Ruiyang Li, Wenben Chen, Mingyuan Li, Ruixin Wang, Lanqin Zhao, Yuanfan Lin, Xinwei Chen, Yuanjun Shang, Xueer Tu, Duoru Lin, Xiaohang Wu, Zhenzhe Lin, Andi Xu, Xun Wang, Dongni Wang, Xulin Zhang, Meimei Dongye, Yunjian Huang, Chuan Chen, Yi Zhu, Chunqiao Liu, Youjin Hu, Ling Zhao, Hong Ouyang, Miaoxin Li, Xuri Li, Haotian Lin   +26 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Public awareness of low vision rehabilitation in China

Frontiers in Medicine
ObjectiveTo demonstrate public awareness of low vision rehabilitation (LVR) in China and identify related influencing factors.MethodsThis cross-sectional study assessed low vision rehabilitation awareness using a Delphi method validated questionnaire ...
Xiaoman Li, Xiaoman Li, Ruyi Zhu, Yuanyuan Liu, Yuanyuan Liu, Jianing Zhang, Jianing Zhang, Xiaoyue Hu, Xiaoyue Hu, Qi Chi, Qi Chi, Na Lin, Na Lin, Jie Chen, Jie Chen   +14 more
doaj   +1 more source