Results 31 to 40 of about 160,176 (268)

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

Factors associated with graft astigmatism after corneal transplantation for keratoconus

BMC Ophthalmology
Background Graft astigmatism remains a major impediment to early visual rehabilitation and the long-term success of keratoplasty. Previous studies have identified graft size, donor–recipient size discrepancy, timing of suture removal, and surgical ...
Sepehr Feizi, Mohammad Ali Javadi, Sina Khosravi Mirzaei, Firouze Hatami, Kia Bayat, Mohammad Abolhosseini, Hamed Esfandiari, Zahra Khorrami   +7 more
doaj   +1 more source

Public awareness of low vision rehabilitation in China

Frontiers in Medicine
ObjectiveTo demonstrate public awareness of low vision rehabilitation (LVR) in China and identify related influencing factors.MethodsThis cross-sectional study assessed low vision rehabilitation awareness using a Delphi method validated questionnaire ...
Xiaoman Li, Xiaoman Li, Ruyi Zhu, Yuanyuan Liu, Yuanyuan Liu, Jianing Zhang, Jianing Zhang, Xiaoyue Hu, Xiaoyue Hu, Qi Chi, Qi Chi, Na Lin, Na Lin, Jie Chen, Jie Chen   +14 more
doaj   +1 more source

The Effect of Ocular Melanin Density on Human Vision

Biomedical and Clinical Research, 2022
Background: Without discussing the effect of ocular melanin density on vision, let us make the logical assumption that since melanin is a protective factor for the eye, its lower density causes more sunlight to damage vision cells. The question is not how the melanin density of the eye affects vision, but how the melanin density of the eye affects ...
openaire   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Corneal backscatter as a biomarker for edema severity in Fuchs endothelial corneal dystrophy: a cross-sectional study

Eye and Vision
Background Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive endothelial dysfunction and corneal edema. Reliable objective biomarkers for grading disease severity are currently evolving.
Maximilian Friedrich, Hyeck-Soo Son, Lasha-Giorgi Turava, Maximilian Hammer, Louise Blöck, Lizaveta Chychko, Timur Mert Yildirim, Gerd Uwe Auffarth, Victor Aristide Augustin   +8 more
doaj   +1 more source

Quantitative interocular suppression in children with intermittent exotropia

Frontiers in Neuroscience, 2023
PurposeWe have demonstrated that the depth of unbalanced interocular suppression can be quantified by balancing the interocular luminance differences required when both eyes are viewing simultaneously.
Hui Chen, Hui Chen, Xiaohui Jiang, Xiaohui Jiang, Weijie Liu, Weijie Liu, Jiawei Zhou, Jiawei Zhou, Jie Chen, Jie Chen, Qianqian Sun, Qianqian Sun, Lin Liang, Lin Liang, Jiangtao Lou, Jiangtao Lou, Xinping Yu, Jia Qu, Jia Qu   +18 more
doaj   +1 more source

Ocular and vision defects in preschool children. [PDF]

British Journal of Ophthalmology, 1993
Ocular and/or vision defects are one of the commonest reasons for the referral of young children to hospital. In a survey of a birth cohort in one health district, 7.1% of children were diagnosed as having such defects by their fifth birthday; 2.1% were detected before the age of 2 years, and 5.1% between 2 and 5 years.
M, Stayte, B, Reeves, C, Wortham
openaire   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source