Results 31 to 40 of about 158,041 (264)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

MicroRNA-21-5p from induced pluripotent stem cells promotes neuroprotection of retinal ganglion cells in optic nerve crush model

BMC Ophthalmology
Introduction Retinal ganglion cells (RGCs) are susceptible to degenerative conditions such as glaucoma and traumatic optic neuropathies, which lead to vision loss.
Qing Xia, Wei Chen, Jiawei Xiong, Xiaofen Mo   +3 more
doaj   +1 more source

Generation of an integration-free induced pluripotent stem cell line (FDEENTi003-A) from a patient with pathological myopia

Stem Cell Research, 2019
Pathological myopia (PM) is a major cause of irreversible vision impairment worldwide. We have successfully reprogrammed the peripheral blood mononuclear cells (PBMCs) from a PM patient to induced pluripotent stem cells and characterized their ...
Xinyue Bai, Xian-Jie Yang, Ling Chen
doaj   +1 more source

DEVELOPMENT AND EVALUATION OF VISION MULTIPLEXING DEVICES FOR VISION IMPAIRMENTS [PDF]

International Journal on Artificial Intelligence Tools, 2009
We have proposed a novel concept of vision multiplexing for the visually impaired – superimposing contour images over their natural view of a scene or over original images presented on a TV screen. We have implemented the concept using an optical see-through head mounted display to provide either visual field expansion to patients with peripheral ...
Eli Peli, Gang Luo 0003, Alex R. Bowers, Noa M. Rensing   +3 more
openaire   +2 more sources

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk

Stem Cell Research & Therapy
Background Stem cell-derived secreted factors could protect neurons in neurodegenerative disease or after injury. The exact neuroprotective components in the secretome remain challenging to discover.
Qing Xia, Kun-Che Chang, Yanan Sun, Michael Nahmou, Takahiko Noro, Yun Cheng, Xiangmei Kong, Xiaofen Mo, Jeffrey L. Goldberg, Suqian Wu   +9 more
doaj   +1 more source

Pediatric Balint’s Syndrome Variant: A Possible Diagnosis in Children

Case Reports in Ophthalmological Medicine, 2016
Balint’s syndrome is well described in adults, but not in children. It is caused by bilateral posterior parietal lobe damage and comprises a triad of simultanagnosia (inability to simultaneously see more than a small number of items), optic ataxia ...
Swetha Sara Philip, Sunithi Elizabeth Mani, Gordon N. Dutton   +2 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Case report: Transmuscular migration of a solid encircling silicone band through all four rectus muscles

Frontiers in Medicine
PurposeWe present a case of transmuscular migration of a solid encircling silicone band through all four rectus muscles.ObservationsA 33-year-old male with high myopia presented with a progressively worsening subclinical peripheral rhegmatogenous retinal
Ruiping Gu, Ruiping Gu, Ruiping Gu, Kaicheng Wu, Kaicheng Wu, Kaicheng Wu, Chunhui Jiang, Chunhui Jiang, Chunhui Jiang   +8 more
doaj   +1 more source