Mapping and characterization of visna/maedi virus cytotoxic T-lymphocyte epitopes
Journal of General Virology, 2008 CD8+cytotoxic T-lymphocyte (CTL) responses have been shown to be important in the control of human and simian immunodeficiency virus infections. Infection of sheep with visna/maedi virus (VISNA), a related lentivirus, induces specific CD8+CTLin vivo, but the specific viral proteins recognized are not known.
Changxin, Wu +3 more
openaire +2 more sources
Vaccination delays maedi-visna lentivirus infection in a naturally-infected sheep flock
BMC Veterinary Research, 2013 Background The Maedi-Visna (MV) lentivirus causes two slowly progressive eventually fatal diseases of sheep, Maedi, a progressive interstitial pneumonia, and Visna, a progressive demyelinating disease of the central nervous system.
Gudnadóttir Margrét +2 more
doaj +1 more source
Evolution of specific antibodies and proviral DNA in milk of small ruminants infected by small ruminant lentivirus [PDF]
, 2013 The diagnosis of Small Ruminant Lentivirus (SRLV) is based on clinical signs, pathological lesions and laboratory testing. No standard reference test for the diagnosis of maedi visna has been validated up to the present, and it is puzzling that tests ...
Arjona, Alvaro +6 more
core +3 more sources
PREVALENCE OF MAEDI-VISNA IN SHEEP HERDS
Archives of Veterinary Medicine, 2008 Progressive sheep pheumonia and maedi are terms that denote chronic virus sheep disease. Maedi-visna virus causes a disease named visna, which is a disease of nervous system with the symptoms of paresis and paralyses.
Branka Vidić +4 more
doaj +1 more source
Experimental infection of sheep with visna/maedi virus via the conjunctival space
Journal of General Virology, 2008 Experiments were performed to determine whether visna/maedi virus (VMV), a small ruminant lentivirus (SRLV), could infect sheep via ocular tissues. The EV1 strain of VMV was administered into the conjunctival space of uninfected sheep, and the animals monitored for the presence of provirus DNA and anti-VMV antibodies in blood.
Niesalla, Heide +4 more
openaire +3 more sources
Diagnosing infection with small ruminant lentiviruses of genotypes A and B by combining synthetic peptides in ELISA [PDF]
, 2015 The major challenges in diagnosing small ruminant lentivirus (SRLV) infection include early detection and genotyping of strains of epidemiological interest.
Amorena Zabalza, Beatriz +9 more
core +1 more source
Mutational analysis of a principal neutralization domain of visna/maedi virus envelope glycoprotein
Journal of General Virology, 2008 We have shown previously that a type-specific neutralization domain is located within a 39 aa sequence in the fourth variable domain of gp135 in visna/maedi virus. We now show that neutralizing antibodies detected early in infection are directed to this epitope, suggesting an immunodominant nature of this domain.
Benedikta S, Haflidadóttir +6 more
openaire +2 more sources
Characterization of the lymphocytic alveolitis in visna-maedi virus-induced interstitial lung disease of sheep [PDF]
Clinical and Experimental Immunology, 1992 SUMMARYIn order to investigate the contribution of lymphocytes to interstitial lung disease in animals with visna-maedi infection, we studied in parallel bronchoalveolar cells and lung tissue from slaughterhouse animals (n = 29) and from colostrum-deprived lambs transtracheally inoculated with field isolates of visna-maedi virus (n = 9) or saline (n ...
G, Cordier +5 more
openaire +2 more sources
Produção de antígeno nucleoprotéico do vírus da artrite-encefalite caprina e comparação com o do vírus Maedi-Visna para utilização em teste de imunodifusão em ágar gel [PDF]
Pesquisa Veterinária Brasileira, 1998 Foi feita uma comparação entre os antígenos (Ag), preparados a partir dos vírus Maedi-Visna (MVV) e Artrite-encefalite Caprina (CAEV) para detecção de anticorpos contra o CAEV em 120 amostras de soro caprino.
Silvio R. O. Abreu +3 more
doaj +1 more source
Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers
Spanish Journal of Agricultural Research, 2014 The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated.
Eider Salazar +10 more
doaj +1 more source