Results 61 to 70 of about 8,011,604 (349)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Does Visual Spatial Awareness Require the Visual Awareness of Space? [PDF]

open access: yes, 2011
Many philosophers have held that it is not possible to experience a spatial object, property, or relation except against the background of an intact awareness of a space that is somehow ‘absolute’. This paper challenges that claim, by analyzing in detail
Schwenkler, Dr. John
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Visual Search [PDF]

open access: yesCurrent Biology, 2000
Visual search is the process of finding things that you are looking for in a world full of things that you are not looking for. Search tasks are ubiquitous. Many are so routine that we do not think of them as search tasks (e.g., Where is the space bar on the keyboard?). Others are more taxing (Where is the cat hiding?) and/or more important (Is there a
openaire   +2 more sources

Auditory-Visual and Visual-Visual Equivalence Relations in Children [PDF]

open access: yesThe Psychological Record, 2005
Previous research has suggested that persons with mental retardation evidence equivalence more readily after being trained on auditory-visual than on visual-visual match-to-sample tasks. The present study sought to determine if this discrepancy is also apparent in normally capable preschoolers and whether the derived class-consistent test performances ...
Smeets, Paul M., Barnes-Holmes, Dermot
openaire   +2 more sources

Spot the Difference! Visual plagiarism in the visual arts. [PDF]

open access: yes, 2012
Over recent years there has been considerable investment in the use of technology to identify sources of text-based plagiarism in universities. However, students of the visual arts are also required to complete numerous pieces of visual submissions for ...
Garrett, Leigh, Robinson, Amy
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Olfactory cue use by three-spined sticklebacks foraging in turbid water: prey detection or prey location? [PDF]

open access: yes, 2012
Foraging, when senses are limited to olfaction, is composed of two distinct stages: the detection of prey and the location of prey. While specialist olfactory foragers are able to locate prey using olfactory cues alone, this may not be the case for ...
Dunn, Alison M.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy