Results 81 to 90 of about 2,005,595 (269)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Frontiers in Neurology, 2019 Motion perception following rotational vestibular stimulation is described either as a self-motion or as an environmental-motion. The purpose of the present study was to establish frequency of occurrence of both sensations in healthy humans; what other ...
Ognyan I. Kolev, Ognyan I. Kolev
doaj +1 more source
Using Visualization to Debug Visualization Software [PDF]
IEEE Computer Graphics and Applications, 2010 This article provides useful strategies for debugging visualization software.The key to debugging visualization software is to exploit the strengths of computer graphics and visualization.
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
"Cutaneous rabbit" hops toward a light: Unimodal and cross-modal causality on the skin
Frontiers in Psychology, 2012 Our somatosensory system deals with not only spatial but also temporal imprecision, resulting in characteristic spatiotemporal illusions. Repeated rapid stimulation at the wrist, then near the elbow, can create the illusion of touch at intervening ...
Tomohisa eAsai, Noriaki eKanayama
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Filming Up: Brazilian Elites Through an Ethnographic Lens [PDF]
Vibrant: Virtual Brazilian AnthropologyThis article is based on the idea of filming up, contextualizing it in both visual anthropology and documentary history. We will first offer a brief analysis of audiovisual production concerning elites to reflect on how they are pictured and how this is ...
Alex Vailati, Walter Andrade
doaj +1 more source
A visual environment for visual languages
Science of Computer Programming, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source