Results 61 to 70 of about 2,024,771 (269)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Prevalence and causes of visual impairment among schoolchildren in Mekelle, Ethiopia
Cogent Medicine, 2018 Purpose: To estimate the prevalence and causes of visual impairment (VI), among primary school children in Mekelle, Ethiopia and the feasibility of teachers conducting vision screening in school using a smart phone application:Peek Acuity.
Usha Dhanesha +3 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2014 The lateral geniculate nucleus is the gateway for visual information en route to the visual cortex. Neural activity is characterized by the existence of 2 firing modes: burst and tonic. Originally associated with sleep, bursts have now been postulated to
Tania eOrtuno +7 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Brain Oscillatory Correlates of Visual Short-Term Memory Errors
Frontiers in Human Neuroscience, 2019 Brain dynamics of memory formation were explored during encoding and retention intervals of a visual working memory task. EEG data were acquired while subjects were exposed to grayscale images of widely known object categories (e.g., “luggage,” “chair ...
Igor Mapelli, Tolga Esat Özkurt
doaj +1 more source
From Visual Query to Visual Portrayal [PDF]
Procedings of the British Machine Vision Conference 2008, 2008 In this paper we show how online images can be automatically exploited for scene visualization and reconstruction starting from a mere visual query provided by the user. A visual query is used to retrieve images of a landmark place using a visual search engine.
Shahrokni, A, Mei, C, Torr, P, Reid, I
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Pedagogia Visuale/Visual Pedagogy [PDF]
Proceedings of the International and Interdisciplinary Conference IMMAGINI? Brixen, Italy, 27–28 November 2017., 2017 Over the twentieth century, visual anthropology and visual sociology defined a way of conducting research which placed the supremacy of the written text as the only scientifically recognised form for collecting and processing empirical data in crisis, affirming the legitimacy of research into visual repertories (photographs, films, videos) deemed as ...
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source