Results 61 to 70 of about 349,442 (310)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
High and Low Contrast Visual Acuity Are Not Affected in Amyotrophic Lateral Sclerosis. [PDF]
PLoS ONE, 2016 The afferent visual system may be affected by neuro-degeneration in amyotrophic lateral sclerosis (ALS) based on observations of visual function impairment and retinal inclusions on histopathology in ALS patients.
Heather E Moss +3 more
doaj +1 more source
What is the global burden of visual impairment? [PDF]
, 2006 Background A recent estimate by the World Health Organization (WHO) suggests that 161 million persons worldwide have visual impairment, including 37 million blind (best-corrected visual acuity less than 3/60 in the better eye) and 124 million with visual
Lalit Dandona, Rakhi Dandona
core +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Long-term evolution of Valsalva retinopathy: a case series [PDF]
, 2012 INTRODUCTION: Valsalva retinopathy may occur as a sudden, dramatic loss of central vision due to the premacular location of the haemorrhage. It has been described in different clinical settings, and there are several options for its treatment.
Carmen González Castaño +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Frontiers in Public HealthPurposeThis study aimed to explore the effects of additional visual tasks in physical exercise on the vision and balance ability of children, and to verify whether children’s vision mediated the influence of physical exercise on their balance ability ...
Rongbin Yin +5 more
doaj +1 more source
High visual acuity revealed in dogs. [PDF]
PLoS ONE, 2017 Humans have selectively bred and used dogs over a period of thousands of years, and more recently the dog has become an important model animal for studies in ethology, cognition and genetics.
Olle Lind +4 more
doaj +1 more source
Distance doubling visual acuity test: A reliable test for nonorganic visual loss [PDF]
, 2018 Background: To determine the value of the distance doubling visual acuity test in the diagnosis of nonorganic visual loss in a comparative observational case series.
Mojon, Daniel, Zinkernagel, Sebastian
core
Foveal visual acuity is worse and shows stronger contour interaction effects for contrast-modulated than luminance-modulated Cs [PDF]
, 2013 Contrast-modulated (CM) stimuli are processed by spatial mechanisms that operate at larger spatial scales than those processing luminance-modulated (LM) stimuli and may be more prone to deficits in developing, amblyopic, and aging visual systems ...
Flom +7 more
core +1 more source