Results 31 to 40 of about 135,801 (215)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

ROLE OF ULTRASOUND THERAPY IN OSTEOARTHRITIS KNEE

open access: yesPakistan Armed Forces Medical Journal, 2018
Objective: To study the role of ultrasound therapy in osteoarthritis of knee joint. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Combined Military Hospital, Okara for a period of 6 months, from Jul 2016 to Dec 2016 ...
Syed Naveed Mumtaz, Syed Hussain Shah
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Effect of Sevoflurane Plus Propofol on Pain and Complications after Laminectomy: A Randomized Double Blind Clinical Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Pain is one of the most important reasons for the patients concern after surgery. The perfect sedative should have properties like rapid onset, least pain and adverse effects.
Aminolah Vasigh   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

A Study to Compare Efficacy of Ultrasound Guided Saphenous Versus Genicular Nerve Block in Osteoarthritis Knee Pain [PDF]

open access: yesInternational Journal of Scientific Research in Dental and Medical Sciences
Background and aim: The most prevalent cause of disability among older persons is osteoarthritis (OA). We compared the efficacy of ultrasound-guided saphenous nerve block (SNB) with genicular nerve block (GNB) in osteoarthritis knee pain.Material and ...
Mangal Ahlawat   +5 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Estimation of utility values from visual analog scale measures of health in patients undergoing cardiac surgery

open access: yesClinicoEconomics and Outcomes Research, 2014
Lars Oddershede,1,2 Jan Jesper Andreasen,1 Lars Ehlers2 1Department of Cardiothoracic Surgery, Center for Cardiovascular Research, Aalborg University Hospital, Aalborg, Denmark; 2Danish Center for Healthcare Improvements, Faculty of Social Sciences and ...
Oddershede L, Andreasen JJ, Ehlers L
doaj  

A Clinical Study of Bee Venom Acupuncture Therapy on External Epicondylitis

open access: yesJournal of Pharmacopuncture, 2006
Objective : This study was to evaluate the effectiveness of Bee Venom acupuncture therapy on external epicondylitis. Methods : We divided chronic arthritis of ankle patient into 2 groups; one group combined bee venom acupuncture therapy and acupuncture
Kyung-Tae Kim, Ho-Sueb Song
doaj   +1 more source

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