Results 51 to 60 of about 301,376 (353)

Evaluation of the Short- and Long-Term Effectiveness of Pulsed Radiofrequency and Conventional Radiofrequency Performed for Medial Branch Block in Patients with Lumbar Facet Joint Pain

Pain Research and Management, 2018
Background. Diagnosis of lumbar facet joint disease is the sum of the combinations consisting of history, physical activity, and diagnostic imaging frequently including computed tomography and magnetic resonance imaging scans.
Abdurrahman Çetin, Abdulkadir Yektaş
doaj   +1 more source

Gonadotrophin-releasing hormone analogue or dienogest plus estradiol valerate to prevent pain recurrence after laparoscopic surgery for endometriosis: a multi-center randomized trial. [PDF]

, 2015
Objectives To evaluate the efficacy of dienogest + estradiol valerate (E2V) and gonadotrophin-releasing hormone analogue (GnRH-a) in reducing recurrence of pain in patients with chronic pelvic pain due to laparoscopically diagnosed and treated ...
Calagna, Gloria, Colacurci, N, CUCINELLA, Gaspare, De Franciscis, P, Granese, R, PERINO, Antonino, Saitta, S, Triolo, O   +7 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study [PDF]

, 2008
<b>Objective</b>: To compare the analgesic efficacy and side effects of the synthetic cannabinoid nabilone with those of the weak opioid dihydrocodeine for chronic neuropathic pain.
Frank, B., Hughes, J., Kapur, D., Matthews, J.N.S., Serpell, M.G.   +4 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Pengaruh Calf Stretching Terhadap Penurunan Nyeri Plantar Fascia Pada Pasien Plantar Fasciitis di RSUD Dr. Moewardi Surakarta [PDF]

, 2018
Background: Plantar fasciitis is a condition of a strong tissue is supporting the arch of the foot becomes irritated or inflamed. This strong tissue is named plantar fascia, a thick bundle of tissue extending along the soles of the feet from the heel to ...
, Agus Widodo, S.Fis., M.Fis, , dr. Siti Soekiswati, M.H, , Umi Budi Rahayu, S.Fis., M.Kes, Maghfiroh, Rinna Ainul   +3 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Effect of Metoclopramide Addition to Lidocaine on Pain of Patients with Grades II and III Post-Episiotomy Repair [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Episiotomy is the most common procedure used for dilatation of the vaginal opening for giving birth. Although episiotomy is associated with benefits for the mother, it may lead to short term and long term disabilities, including ...
Sheida Shabanian, Sara Kalbasi, Gholamreza Shabanian, Bahram Khoram, Forozan Ganji   +4 more
doaj   +1 more source

Perioperative anxiolysis and analgesic effect after premedication with melatonin and pregabalin in total hip arthroplasty under spinal anaesthesia: A prospective comparative trial

Advanced Biomedical Research, 2023
Background: Preoperative anxiety plays a critical role in post-operative pain response and other outcomes. Melatonin is a naturally secreted hormone which has anxiolytic, sedative, and analgesic properties.
Akash Mishra, Vinod Kumar Srivastava, Ravi Prakash, Neel Kamal Mishra, Jyotsna Agarwal, Shruti Kabi   +5 more
doaj   +1 more source

Validity and Responsiveness of the Visual Vertigo Analogue Scale

Journal of Neurologic Physical Therapy, 2019
Background and Purpose: People with visual vertigo have dizziness provoked by visual stimulation. We have developed a Visual Vertigo Analogue Scale (VVAS) to evaluate their symptoms and response to rehabilitation. Our goal was to validate the VVAS against the Situation Characteristics Questionnaire (SITQ) score and determine ...
Gevorg Chilingarian, Joyce Fung, Elizabeth Dannenbaum   +2 more
openaire   +3 more sources