Results 81 to 90 of about 1,910,657 (313)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Analysis and Visualization of Tree Space [PDF]
We explored the use of multidimensional scaling (MDS) of tree-to-tree pairwise distances to visualize the relationships among sets of phylogenetic trees. We found the technique to be useful for exploring "tree islands" (sets of topologically related trees among larger sets of near-optimal trees), for comparing sets of trees obtained from bootstrapping ...
David M, Hillis +2 more
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
This article conceptualizes active tourism as a strategy for promoting physical activity (PA) among children and adolescents and examines the literature that has analyzed its different modalities and their application across diverse settings and contexts.
Emilio Martínez-Redecillas +3 more
doaj +1 more source
Using Visual Tools for Analysis and Learning
This pack is intended as a resource for lecturers and students to facilitate the further development of their learning and teaching strategies. Visual tools were initially introduced within a module of the Year 3 nursing curriculum within the University ...
Burton, Rob +2 more
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Anticipation of Turn-switching in Auditory-Visual Dialogs
Mixdorff H, Hönemann A, Kim J, Davis C. Anticipation of Turn-switching in Auditory-Visual Dialogs.
Hönemann, Angelika +5 more
core
Motion computation and visual orientation in flies
Egelhaaf M, Borst A. Motion computation and visual orientation in flies. Comparative Biochemistry and Physiology, A: Comparative Physiology. 1993;104(4):659-673.Visual orientation greatly relies on the evaluation of the motion patterns received by the ...
Egelhaaf, M. +3 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Landscape semiotics and visual / textual analysis in Anglo-American cultural geography
The article focuse is on the landscape understanding from the perspective of semiotics and critical social theory in Anglo-American cultural geography and the method of landscape visual/textual analysis.
Roman Lozynskyi
doaj +1 more source

