Results 91 to 100 of about 5,112,987 (375)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Process Mining Meets Visual Analytics: The Case of Conformance Checking [PDF]

open access: green, 2022
Jana-Rebecca Rehse   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Does Culture Shape Our Spatial Ability? An Investigation Based on Eye Tracking

open access: yesISPRS International Journal of Geo-Information, 2022
Culture affects people’s spatial memory, mental representations, and spatial reference frameworks. People with different cultural backgrounds show different degrees of spatial ability.
Yuyang Tian, Tianyu Yang, Weihua Dong
doaj   +1 more source

Can you tell a face from a HEVC bitstream?

open access: yes, 2017
Image and video analytics are being increasingly used on a massive scale. Not only is the amount of data growing, but the complexity of the data processing pipelines is also increasing, thereby exacerbating the problem.
Alvar, Saeed Ranjbar   +2 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Designing a System Architecture for Dynamic Data Collection as a Foundation for Knowledge Modeling in Industry

open access: yesApplied Sciences
This study develops and implements a scalable system architecture for dynamic data acquisition and knowledge modeling in industrial contexts. The objective is to efficiently process large datasets to support decision-making and process optimization ...
Edmund Radlbauer   +2 more
doaj   +1 more source

Steering data quality with visual analytics: The complexity challenge

open access: yesVisual Informatics, 2018
Data quality management, especially data cleansing, has been extensively studied for many years in the areas of data management and visual analytics. In the paper, we first review and explore the relevant work from the research areas of data management ...
Shixia Liu   +7 more
doaj   +1 more source

Maleku: an evolutionary visual software analytics tool for providing insights into software evolution [PDF]

open access: yes, 2011
Software maintenance is a complex process that requires the understanding and comprehension of software project details. It involves the understanding of the evolution of the software project, hundreds of software components and the relationships among ...
García-Peñalvo, Francisco   +4 more
core  

Exploring the Design Space of Immersive Urban Analytics

open access: yes, 2017
Recent years have witnessed the rapid development and wide adoption of immersive head-mounted devices, such as HTC VIVE, Oculus Rift, and Microsoft HoloLens.
Chen, Wei   +7 more
core   +3 more sources

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