Results 81 to 90 of about 2,285,675 (298)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Visual Analytics: A Comprehensive Overview
IEEE Access, 2019 With the ever-increasing amount of data, the world has stepped into the era of “Big Data”. Presently, the analysis of massive and complex data and the extraction of relevant information, have been become essential tasks in many fields of ...
Wenqiang Cui
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A Visual Analytics System for Managing Mobile Network Failures
, 2018 Large mobile operators have to quickly react to mobile network failures to ensure service continuity and this task is a complex one, due to the continuous and very fast evolution of mobile networks: from 2G to 3G and onto LTE, each significant milestone ...
Mirabelli, Mario +7 more
core +1 more source
VISUAL AND ANALYTIC STRATEGIES IN GEOMETRY
Frontline Learning Research, 2016 We argue that there is an increasing reliance on analytic strategies compared to visuo-spatial strategies, which is related to geometry expertise and not on individual differences in cognitive style. A Visual/Analytic Strategy Test (VAST) was developed to investigate the use of visuo-spatial and analytic strategies in geometry in 30 mathematics ...
Kospentaris, G. +3 more
openaire +4 more sources
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
VISLA: Visual aspects of learning analytics
, 2022 S.394-395In this paper, we briefly describe the goal and activities of the LAK15 workshop on Visual Aspects of Learning ...
Pardo, Abelardo +8 more
core +1 more source
User Evaluation of Map-Based Visual Analytic Tools
ISPRS International Journal of Geo-Information, 2019 Big data have also become a big challenge for cartographers, as the majority of big data may be localized. The use of visual analytics tools, as well as comprising interactive maps, stimulates inter-disciplinary actors to explore new ideas and decision ...
Stanislav Popelka +7 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source