Results 91 to 100 of about 2,285,675 (298)
, 2013 Der Umfang der weltweit aufgenommenen Videodaten wächst stark und hat bereits Dimensionen erreicht, die schwer handhabbar sind. Die Videodaten stammen dabei aus verschiedensten Anwendungsgebieten, wie beispielsweise der Videoüberwachung, Sportanalyse, wissenschaftlichen Videoanalyse, Operationsdokumentation und der Unterhaltung, und deren Analyse ist ...
openaire +3 more sources
Species habitat modeling based on image semantic segmentation
Scientific ReportsHabitat monitoring has emerged as a crucial practice for preserving ecological environments and ensuring species reproduction. Traditional habitat modeling often relies on the “lasagna model”—a McHarg-style approach that focuses on the ecological niche ...
Lingjun Wang +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2016 A pdf. copy of Cognos Analytics home page is not available for public view on SOAR.
IBM Analytics
core
Learning analytics architecture to scaffold learning experience through technology-based methods [PDF]
, 2015 The challenge of delivering personalized learning experiences is often increased by the size of classrooms and online learning communities. Serious Games (SGs) are increasingly recognized for their potential to improve education.
Manuel Ninaus +55 more
core +1 more source
Visual Analytics of Paleoceanographic Conditions [PDF]
2006 IEEE Symposium On Visual Analytics And Technology, 2006 Decade scale oceanic phenomena like El Ni no are correlated with weather anomalies all over the globe. Only by understanding the events that produced the climatic conditions in the past it will be possible to forecast abrupt climate changes and prevent disastrous consequences for human beings and their environment.
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source