Results 61 to 70 of about 13,004 (278)

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Bi-sinusoidal light stimulation reveals an enhanced response power and reduced phase coherence at the visual cortex in migraine

Frontiers in Neurology
IntroductionMigraine is associated with enhanced visual sensitivity during and outside attacks. Processing of visual information is a highly non-linear process involving complex interactions across (sub)cortical networks.
Thomas C. van den Hoek, Matthijs J. L. Perenboom, Gisela M. Terwindt, Else A. Tolner, Else A. Tolner, Mark van de Ruit, Mark van de Ruit   +6 more
doaj   +1 more source

Brain networking analysis in migraine with and without aura

The Journal of Headache and Pain, 2017
Background To apply effective connectivity by means of nonlinear Granger Causality (GC) and brain networking analysis to basal EEG and under visual stimulation by checkerboard gratings with 0.5 and 2.0 cpd as spatial frequency in migraine with aura (MA ...
Marina de Tommaso, Gabriele Trotta, Eleonora Vecchio, Katia Ricci, R. Siugzdaite, Sebastiano Stramaglia   +5 more
doaj   +1 more source

Microstructure Reconstruction in Battery Electrodes Using Machine Learning Based on Low‐Voltage Focused Ion Beam–Scanning Electron Microscopy Tomography Images

Advanced Engineering Materials, EarlyView.
Low‐voltage FIB‐SEM tomography combined with a image preprocessing pipeline improves phase contrast and enables reliable machine‐learning segmentation of conductive networks in lithium‐ion battery electrodes. Structural descriptors are extracted from segmented images, done semimanually and automated, and compared.
Lisa Beran, Vincent Nebel, Dominik Perius, Kshitij Kumar, Yannis Heim, Laura Bies, Tobias Kraus   +6 more
wiley   +1 more source

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing [PDF]

, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Laucht, Manfred (Prof. Dr.), Rellum Thomas, Thomas Rellum, Resch, Franz, Stephan Bender, Brandeis, Daniel, Banaschewski, Tobias, Laucht Manfred, Bender, Stephan, Rietschel, Marcella, Jennen-Steinmetz, Christine, Freitag, Christine M., Treutlein, Jens, Jens Treutlein, Rellum, Thomas, Daniel Brandeis, Brandeis Daniel, Tobias Banaschewski, Jennen-Steinmetz Christine, Christine Freitag, Bender Stephan, Banaschewski Tobias, Manfred Laucht, Freitag, Christine, Franz Resch, Rietschel Marcella, Marcella Rietschel, Resch Franz, Christine Jennen-Steinmetz, Laucht, Manfred, Treutlein Jens, Freitag Christine   +31 more
core   +1 more source

Migraine with aura: less control over pain and fragrances?

The Journal of Headache and Pain, 2023
Background Accumulating data emphasizes the importance of olfaction in migraine pathophysiology. However, there are only a few studies evaluating how the migraine brain processes olfactory stimulation, and virtually no studies comparing patients with and
Coralie Mignot, Vanda Faria, Thomas Hummel, Marie Frost, Christoph M. Michel, Gudrun Gossrau, Antje Haehner   +6 more
doaj   +1 more source

In Situ Crystalline‐Amorphous Composite Oxide Structure Suppressing Thermal Wear Instability for Refractory Multi‐Principal Element Alloy

Advanced Functional Materials, EarlyView.
An effective strategy is developed to overcome the medium temperatures wear resistance degradation in refractory multi‐principal element alloys. By utilizing chemical short‐range ordering to trigger oxygen‐induced amorphization, a composite oxide structure is formed, which combines high hardness with robust stiffness.
Xuhui Pei, Jianbao Zhang, Hanming Wang, Yin Du, Tao Yang, Ji‐Jung Kai, Benyebka Bou‐Saïd, Haifeng Wang   +7 more
wiley   +1 more source

Hybrid Solar Cell/Triboelectric Nanogenerator Based on Stable Two‐Dimensional Covalent Organic Frameworks

Advanced Functional Materials, EarlyView.
This study highlights the integration of stable two‐dimensional covalent organic framework (COF) films as photoactive layers in hybrid nanoenergy devices. The results demonstrate their capacity to generate electricity under both sunny and rainy conditions, showcasing versatility and resilience.
Joab D. Guerrero, Susana Ramos‐Terrón, Salvador R. G. Balestra, José M. Malagón, David Aparicio, Lucia Velasco, Asterios Charisiadis, Dooshaye Moonshiram, Margarita Darder, Pilar Aranda, Bernd Wicklein, Gustavo de Miguel, Javier Pérez‐Carvajal, Eva M. García‐Frutos   +13 more
wiley   +1 more source

BOLD repetition enhancement in the orbitofrontal cortex during complex visuospatial processing in migraine without aura: a shift in periaqueductal gray - cortical coupling? [PDF]

J Headache Pain
Background Visual discomfort and sensory overload are common complaints in migraine patients without aura (MwoA), even between attacks, yet their neural basis remains poorly understood. We aimed to explore brain activation patterns in response to complex
Onlat ZC, Ustun S, Guzel I, Akgor MC, Kolenoglu H, Vuralli D, Alkan S, Çiçek M, Bolay H.   +8 more
europepmc   +2 more sources

First FHM3 mouse model shows spontaneous cortical spreading depolarizations

Annals of Clinical and Translational Neurology, 2020
Here we show, for the first time, spontaneous cortical spreading depolarization (CSD) events – the electrophysiological correlate of the migraine aura – in animals by using the first generated familial hemiplegic migraine type 3 (FHM3) transgenic mouse ...
Nico A. Jansen, Anisa Dehghani, Margot M. L. Linssen, Cor Breukel, Else A. Tolner, Arn M. J. M. van denMaagdenberg   +5 more
doaj   +1 more source