Results 41 to 50 of about 6,080,881 (271)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Art and Visual Culture: A Reader
, 2012 Art & Visual Culture: A Reader is an essential sourcebook for every student of art history, and ideal for anyone seeking a greater understanding of art and of the cultural and historical context in which it is made.
core +5 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
SensorsThis article investigates the impact of visual color perception on fine-grained emotion prediction in videos, analyzing the contribution of color perception features in fine-grained emotion prediction.
Shuang Wang +6 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Medien & ZeitThis article re-examines the Heldenplatz scandal of 1988, long considered the most explosive theatrical controversy of Austria’s Second Republic. While the scandal has often been framed in terms of collective repression and psychoanalytic “working ...
Gal Hertz
doaj +1 more source
Humanities, 2018 The role of photography and social media have been seen as pivotal to the Egyptian political uprisings of 2011 where icons of the revolution circulated widely, helped galvanize protesters, and documented key events against the backdrop of a rapidly ...
Dalia Habib Linssen
doaj +1 more source
Analysis of the inscriptions as advertising media in Persian architecture [PDF]
نگره, 2017 This study seeks to analyze the inscriptions as advertising media in Persian architecture. The purpose of the study, analysis and recognition of the importance of inscriptions finally signifying the place as advertising media, visual identification paper
Aleme Taghizade +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source