Results 41 to 50 of about 629,636 (267)

Rapid and reliable diagnosis of Moraxella catarrhalis infection using loop-mediated isothermal amplification-based testing

Frontiers in Bioengineering and Biotechnology
Moraxella catarrhalis (M. catarrhalis) was an important pathogen closely associated with respiratory tract infections. We employed the loop-mediated isothermal amplification (LAMP) coupled with nanoparticle-based lateral flow biosensor (LFB) and ...
Fei Xiao, Juan Zhou, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Zheng Xu, Yi Wang, Lei Yu, Lihui Meng   +9 more
doaj   +1 more source

A Comparative Study on Visual Detection of Mycobacterium tuberculosis by Closed Tube Loop-Mediated Isothermal Amplification: Shedding Light on the Use of Eriochrome Black T

Diagnostics, 2023
Loop-mediated isothermal amplification is a promising candidate for the rapid detection of Mycobacterium tuberculosis. However, the high potential for carry-over contamination is the main obstacle to its routine use. Here, a closed tube LAMP was intended
Alireza Neshani, Hosna Zare, Hamid Sadeghian, Hadi Safdari, Bamdad Riahi-Zanjani, Ehsan Aryan   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Two-Phase Super-Resolution Quantization Scheme Optimized by Sequential Grading and Data Bias Correction [PDF]

Jisuanji gongcheng
Model quantization technology effectively reduces model storage and computational overhead by mapping high-precision floating-point data to low-bit discrete spaces.
HAO Liang, SU Bohejun, WANG Jinghua, XU Yong
doaj   +1 more source

Visual Detection and Image Processing of Parking Space Based on Deep Learning

Sensors, 2022
The automatic parking system based on vision is greatly affected by uneven lighting, which is difficult to make an accurate judgment on parking spaces in the case of complex image information.
Chen Huang, Shiyue Yang, Yugong Luo, Yongsheng Wang, Ze Liu   +4 more
doaj   +1 more source

Principles of visual motion detection [PDF]

Trends in Neurosciences, 1989
Motion information is required for the solution of many complex tasks of the visual system such as depth perception by motion parallax and figure/ground discrimination by relative motion. However, motion information is not explicitly encoded at the level of the retinal input. Instead, it has to be computed from the time-dependent brightness patterns of
Borst, Alexander, Egelhaaf, Martin
openaire   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Facile Synthesis of Iron and Nitrogen Co-Doped Carbon Dot Nanozyme as Highly Efficient Peroxidase Mimics for Visualized Detection of Metabolites

Molecules, 2023
Visual detection based on nanozymes has great potential for the rapid detection of metabolites in clinical analysis or home-based health management.
Shuai Xu, Shiyue Zhang, Yutong Li, Jiyang Liu   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source