Results 61 to 70 of about 668,131 (266)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Research Progress and Development Trend of Visual Detection Methods for Selective Fruit Harvesting Robots

Agronomy
The rapid development of artificial intelligence technologies has promoted the emergence of Agriculture 4.0, where the machines participating in agricultural activities are made smart with the capacities of self-sensing, self-decision-making, and self ...
Wenbo Wang, Chenshuo Li, Yidan Xi, Jinan Gu, Xinzhou Zhang, Man Zhou, Yuchun Peng   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Portable, precise, and RNA extraction-free: RT-RAA technology for rapid early RSV identification and prevention

Frontiers in Cellular and Infection Microbiology
The Respiratory Syncytial Virus (RSV) is a significant agent linked to respiratory infections, representing a considerable health risk for vulnerable populations, including infants, older adults, and those with weakened immune systems.
Zhenfei Wang, Jing Zhang, Xiao He, Chunming Wang, Zhenyue Li, Zitong Yang, Cheng Zhang, Tingli Fan, Kai Su   +8 more
doaj   +1 more source

Industrial Smoke Detection and Visualization

CoRR, 2018
As sensing technology proliferates and becomes affordable to the general public, there is a growing trend in citizen science where scientists and volunteers form a strong partnership in conducting scientific research including problem finding, data collection, analysis, visualization, and storytelling.
Yen-Chia Hsu, Paul Dille, Randy Sargent, Illah R. Nourbakhsh   +3 more
openaire   +3 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Facile Fluorescent Visualization Method Based on Copper Clusters for Formaldehyde Detection

Molecules
Establishing a simple and effective method for the visual detection of formaldehyde plays an important role in environmental emergency monitoring. In this work, L-cysteine-stabilized copper clusters were synthesized via a green, mild, and facile one-step
Jie Zou, Qing Chen, Guimin Mu, Miao Ma, Fang Yang, Mengtian Li, Fujian Xu, Hui Xia   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A rapid and visual dual LAMP-LFD assay for on-site simultaneous detection of influenza A virus (H1N1) and respiratory syncytial virus (RSV)

Frontiers in Microbiology
Respiratory tract infections caused by influenza A virus (IAV) and respiratory syncytial virus (RSV) are a major global health burden. To overcome the limitations of existing diagnostic techniques for timely detection (point-of-care testing), this study ...
Alang Zhang, Xingyu Lan, Hengxuan Zhou, Ting Zhou, Zhihua Xu, Xinyu Cheng, Chenxi Guo, Mingjie Wei, Jiahui Wu, Feng Shi   +9 more
doaj   +1 more source