Results 81 to 90 of about 631,966 (266)

Industrial Smoke Detection and Visualization

CoRR, 2018
As sensing technology proliferates and becomes affordable to the general public, there is a growing trend in citizen science where scientists and volunteers form a strong partnership in conducting scientific research including problem finding, data collection, analysis, visualization, and storytelling.
Yen-Chia Hsu, Paul Dille, Randy Sargent, Illah R. Nourbakhsh   +3 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Aging and visual pattern detection

Journal of Vision
A single psychophysical experiment evaluated observers' ability to detect visual patterns embedded in noise; effects of stimulus complexity and observer age were also evaluated. Eighteen younger and older observers participated in the experiment (mean ages were 20.3 and 72.6 years, respectively).
Norman, J. Farley, Graham, Jiali D., Eaton, Jerica R.   +2 more
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Cascaded RPA-SDA Amplification Strategy on a Sliding Microfluidic Chip for the Ultrasensitive and Rapid Detection of Shigella

Foods
In this study, a sliding microfluidic biosensor integrating RPA-SDA cascaded amplification was developed for the rapid, visual detection of Shigella. A novel RPA primer targeting the specific ipaH gene was designed to include a 5′-end G-quadruplex (G4 ...
Nali Zhou, Guorong Fan, Nan Yang, Tao Xu, Yunlong Zhang, Wentao Xu, Ying Shang   +6 more
doaj   +1 more source

Visual Attention and Change Detection.

, 2011
Studies suggest that visual attention, guided in part by features’ visual salience, is necessary for change detection. An image processing algorithm was used for measuring the visual salience of the features of scenes, and participants’ ability to detect changes made to high and low salience features was measured with a flicker paradigm while their
Boyer, Ty W., Smith, Thomas G., Yu, Chen, Bertenthal, Bennett I.   +3 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Development of a dual-target RAA-LFD assay for point-of-care and visual detection of Salmonella pullorum and Salmonella typhimurium in fecal samples

Frontiers in Veterinary Science
To address the need for rapid detection of Salmonella pullorum (S. pullorum) and Salmonella typhimurium (S. typhimurium) in the poultry industry, we developed a dual-target point-of-care system integrating recombinase-aided amplification (RAA) with ...
Weiye Zuo, Congxue Shao, He Qin, Hongwei Gao, Xuemei Sun, Pengyan Wang, Jingjing Ren   +6 more
doaj   +1 more source

The detection of visual defects in infants.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
The early warning signs for the detection of visual defects in infants are emphasised. Th~ simple tests which can be carried out by the general practitioner are considered, and the more sophisticated ophthalmic investigations are discussed.S. Afr. Med. J., 48, 1261 (1974).
openaire   +3 more sources