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Introduction. Visual elements, including tables, figures, and diagrams, are a routine feature of contemporary research articles. Previous scholarship has described their formal properties and has documented the prevalence of descriptive commentary, yet ...
Elena V. Tikhonova, Maria A. Grigorieva
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We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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The urban milieu of a campus comprises an intricate constitution of interconnected elements that collectively shape a complex environment. The interrelationships among these elements play a pivotal role in the design of an efficient and sustainable urban
and Emad Hani Ismaeel
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Visual Elements in the Discourse on Information Technology [PDF]
Discourse is critical to organizations as well as to information technology in a variety of ways, as the literature attests (Alvesson and Karreman 2000; Beech 2000; Benders et al. 1998; Button and Sharrock 1995; Oswick et al. 2000; Rachel and Woolgar 1994). But there is an interesting new catch: the ways we talk about technology, and the content of the
Yakura, E +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
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NOTICEABILITY AND RECALL OF VISUAL ELEMENTS ON PACKAGING
Product packaging protects the content from the environment, but also serves to display information relevant to consumers. Some product information, like warning messages, should be both noticeable and memorable. The purpose of the study was to explore how people pay attention to visual elements on packaging and how well they recall them.
Dorotea Kovačević, Maja Brozović
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