Results 71 to 80 of about 357,352 (262)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Effects of Package Design Visual Density and Consumers’ Environmental Consciousness on Choice Intention:

open access: yesMaketingu rebyu
Product packaging is often referred to as a “silent salesman,” and prior research has shown that it exerts a significant influence on consumer purchasing behavior.
Midori Otobe, Yumi Kamada
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

What kind of intuition for what kind of education: A scoping review

open access: yesEncyclopaideia
The general purpose of this scoping review is to investigate the role of intuition in Higher Education. In particular, it aims to understand the contribution of intuition to achieving disciplinary objectives.
Rosa Cera, Marta Sinclair
doaj   +1 more source

Visual Elements of Islam Prophet (PBUH) life events in religious paintings of Jameá- al-Tawarikh [PDF]

open access: yesهنر اسلامی, 2016
Illustration of historical and religious scenes is of high significance in Islamic versions of Iran’s illustration; different features have been manifested in these pictures during different periods of art.
Mahnaz Shayestehfar, .. ..
doaj  

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