Results 41 to 50 of about 111,651 (309)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A comparative study on visual evoked potential in normotensive and hypertensive individuals

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Hypertensive retinopathy is one of the most common complications of hypertension. Hypertension can cause changes in vascular endothelium including hyalinization, which can lead to demyelination of the optic nerve and results in conduction ...
Arunkumar Balakrishnan, Nirmala Natarajan   +1 more
doaj   +1 more source

Influence of Rotating Shift Work on Visual Reaction Time and Visual Evoked Potential [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: The present day life style is changing the circadian rhythm of the body especially in rotating night shift workers. The impact of this prolongs their reaction time.
HEMAMALINI R.V., KRISHNAMURTHY N, SARAVANAN A   +2 more
doaj   +1 more source

Event-related alpha suppression in response to facial motion [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.While biological motion refers to both face and body movements, little is known about the visual perception of facial motion. We therefore examined alpha wave suppression
Michael J. Wright (524298), Spencer Janine V., Christine Girges, Girges, C, Michael J Wright, Janine V. Spencer (524299), Wright, MJ, Spencer, JV, O'Brien, JMD, O’Brien Justin M. D., O'Brien, J, Janine V Spencer, Justin M. D. O’Brien (524300), Girges Christine, Justin M D O'Brien, Spencer, J, Christine Girges (524297), Wright, M, O’Brien, JMD, Wright Michael J.   +19 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Visual Evoked Potential in Multiple Sclerosis

Advanced Medical Journal
Background and objectives: Multiple sclerosis, a neurological disease with or without optic neuritis may cause abnormal visual evoked potential finding.
Asia Ali Rashid , Kamaran Hasan Azeez, Bakhtiar Qadir Hamasalih   +2 more
doaj   +1 more source

Electrophysiological study of thyroid ocular disorders

Delta Journal of Ophthalmology, 2019
Purpose The aims of this study were to evaluate the visual evoked potential (VEP) changes in thyroid ocular disorders and to correlate between VEP latencies and thyroid hormones.
Mona Abdel Kader, Naglaa Abass
doaj   +1 more source

Age-related differences in the transient and steady state responses to different visual stimuli

Frontiers in Aging Neuroscience, 2022
ObjectiveBrain-computer interface (BCI) has great potential in geriatric applications. However, most BCI studies in the literature used data from young population, and dedicated studies investigating the feasibility of BCIs among senior population are ...
Xin Zhang, Yi Jiang, Yi Jiang, Wensheng Hou, Ning Jiang, Ning Jiang   +5 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Stimulus Design for Visual Evoked Potential Based Brain-Computer Interfaces

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Visual stimuli design plays an important role in brain-computer interfaces (BCIs) based on visual evoked potentials (VEPs). Variations in stimulus parameters have been shown to affect both decoding accuracy and subjective perception experience, implying ...
Haoyin Xu, Sheng-Hsiou Hsu, Masaki Nakanishi, Yufan Lin, Tzyy-Ping Jung, Gert Cauwenberghs   +5 more
doaj   +1 more source