TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara +18 more
wiley +1 more source
Developmental sensory experience balances cortical excitation and inhibition. [PDF]
Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of postnatal ...
Barker, Alison J +4 more
core +6 more sources
Subjective Assessment of Visual Function Using Pattern Visual Evoked Potential and Multifocal Visual Evoked Potential: A Case Report [PDF]
doaj +1 more source
Effect of smoking on visual evoked potential (VEP) and visual reaction time (VRT)
Background: Nicotine in tobacco smoke causes demyelination. Again, hypoxia in long-term smokers is linked to neuropathy. Visual receptors are early sufferer of neuropathy.
Karishma Rajbhandari Pandey +4 more
doaj +1 more source
Malleability of the self: electrophysiological correlates of the enfacement illusion [PDF]
Self-face representation is fundamentally important for self-identity and self-consciousness. Given its role in preserving identity over time, self-face processing is considered as a robust and stable process.
Aglioti, Salvatore Maria +4 more
core +2 more sources
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. [PDF]
To uncover the circuit-level alterations that underlie atypical sensory processing associated with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1-/-) mouse model of Fragile X syndrome.
A Contractor +53 more
core +2 more sources
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Increased Latency of Visual Evoked Potentials in Healthy Women during Menstruation
Purpose: To evaluate the latency of visual evoked potentials (VEPs) in healthy women during and after menstruation. Methods: Pattern and flash VEPs were performed in 15 healthy women aged 18 to 25 years on the maximum bleeding day (luteal phase) and 7 ...
Mohsen Azarmina +2 more
doaj

